Asian stocks lower after Pfizer cuts vaccine shipment plans

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In this photo provided by the New York Stock Exchange, specialist James Denaro works at his post on the trading floor, Thursday Dec. 3, 2020. U.S. stocks are inching further into record heights Thursday, as Wall Street continues to coast following its rocket ride last month powered by hopes for coming COVID-19 vaccines. (Nicole Pereira/New York Stock Exchange via AP)

BEIJING (AP) — Asian stock markets followed Wall Street lower Friday after Pfizer Inc. cut the number of doses of a planned coronavirus vaccine it might ship this year.

Benchmarks in Shanghai, Tokyo and Hong Kong, which are the bulk of the region's market value, retreated while Sydney advanced.

Wall Street's benchmark S&P 500 index closed 0.1% lower on Thursday, short of a new record, after Pfizer reduced the number of vaccine doses it might ship this year by half to 50 million. The company told The Wall Street Journal testing and setting up a supply chain took longer than expected.

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Also Thursday, U.S. health authorities reported a one-day record of 3,157 virus deaths.

“Before we can make new gains, there is the usual sentiment tug of war between medium-term optimism and near-term COVID-19 despair,” Stephen Innes of Axi said in a report.

The Shanghai Composite Index lost 0.4% to 3,430.03 and the Nikkei 225 in Tokyo sank 0.3% to 26,727.17. The Hang Seng in Hong Kong retreated 0.2% to 26,686.54.

The Kospi in Seoul gained 1.4% to 2,734.37 and Sydney's S&P-ASX 200 was 0.4% higher at 6,644.00. New Zealand and Jakarta declined while Singapore and Bangkok advanced.

Investors hopeone or more coronavirus vaccines might be available next year despite the challenges of making and distributing billions of doses that must be kept frozen.

On Wall Street, the S&P 500 slipped to 3,666.72. The Dow Jones Industrial Average gained 0.3% to 29,969.52. The Nasdaq composite added 0.2% to 12,377.18.

Investors have been encouraged by signs Democrats and Republicans in Washington may get past their bitter partisanship to agree on an economic aid package.

House Speaker Nancy Pelosi and Senate Majority Leader Mitch McConnell spoke Thursday after Pelosi signaled a willingness to make major concessions. President-elect Joe Biden urged Congress on Wednesday to pass a relief bill now, with more aid to come next year.

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An industry group reported Thursday that U.S. service industries grew in November but the pace slowed for a second month.

The Institute for Supply Management's index of services activity declined to 55.9 from October's 56.6. Readings above 50 represent expansion in industries such as restaurants and bars, retail stores and delivery companies.

A separate report said fewer Americans filed for unemployment benefits last week than forecast, though economists cautioned that number may have been distorted by the Thanksgiving Day holiday.

Oil prices edged higher after OPEC and allied countries including Russia agreed Thursday to increase oil production by 500,000 barrels per day starting from January. They slashed output earlier to shore up price as the pandemic and controls on business and travel depressed demand.

Benchmark U.S. crude gained 71 cents to $46.35 per barrel in electronic trading on the New York Mercantile Exchange. The contract rose 36 cents on Thursday to $45.64 a barrel. Brent crude, used to price international oils, was 90 cents higher at $49.61 per barrel in London. It added 46 cents the previous session to $48.71 a barrel.

The dollar declined to 103.91 yen from Thursday's 103.97 yen. The euro was unchanged at $1.2143.

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