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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:IRD NASDAQ:PBYI NASDAQ:PMN NASDAQ:SRZN On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeIRDOpus Genetics$4.97-1.2%$4.99$0.90▼$5.81$409.42M0.62964,353 shs905,466 shsPBYIPuma Biotechnology$7.19+0.3%$6.86$2.85▼$7.90$364.95M1.24296,945 shs251,403 shsPMNPromis Neurosciences$10.58+0.1%$14.30$6.27▼$39.75$94.79M-0.242,226 shs18,481 shsSRZNSurrozen$29.87-0.9%$28.76$5.90▼$35.00$349.94M0.59110,545 shs14,861 shsBeginner's Guide To Retirement StocksClick the link to see MarketBeat's list of seven best retirement stocks and why they should be in your portfolio. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceIRDOpus Genetics-1.19%-7.28%-10.45%+36.54%+423.16%PBYIPuma Biotechnology+0.28%-0.96%-5.02%+5.43%+147.93%PMNPromis Neurosciences+0.09%+7.63%-12.20%-30.62%-16.20%SRZNSurrozen-0.90%-2.86%-6.22%+22.02%+359.54%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeIRDOpus Genetics$4.97-1.2%$4.99$0.90▼$5.81$409.42M0.62964,353 shs905,466 shsPBYIPuma Biotechnology$7.19+0.3%$6.86$2.85▼$7.90$364.95M1.24296,945 shs251,403 shsPMNPromis Neurosciences$10.58+0.1%$14.30$6.27▼$39.75$94.79M-0.242,226 shs18,481 shsSRZNSurrozen$29.87-0.9%$28.76$5.90▼$35.00$349.94M0.59110,545 shs14,861 shsBeginner's Guide To Retirement StocksClick the link to see MarketBeat's list of seven best retirement stocks and why they should be in your portfolio. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceIRDOpus Genetics-1.19%-7.28%-10.45%+36.54%+423.16%PBYIPuma Biotechnology+0.28%-0.96%-5.02%+5.43%+147.93%PMNPromis Neurosciences+0.09%+7.63%-12.20%-30.62%-16.20%SRZNSurrozen-0.90%-2.86%-6.22%+22.02%+359.54%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceIRDOpus Genetics 2.79Moderate Buy$10.20105.23% UpsidePBYIPuma Biotechnology 2.00HoldN/AN/APMNPromis Neurosciences 2.33Hold$26.50150.47% UpsideSRZNSurrozen 2.80Moderate Buy$42.0040.61% UpsideCurrent Analyst Ratings BreakdownLatest PMN, PBYI, IRD, and SRZN Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/13/2026IRDOpus Genetics Citizens JmpSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetMarket Outperform$12.00 ➝ $11.005/12/2026IRDOpus Genetics Zacks ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingDowngradeHold ➝ Strong Sell5/11/2026PBYIPuma Biotechnology Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingDowngradeHold (C+) ➝ Hold (C)5/7/2026SRZNSurrozen HC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$36.00 ➝ $44.004/30/2026IRDOpus Genetics B. Riley FinancialSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy4/28/2026IRDOpus Genetics CitigroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageOutperform4/28/2026IRDOpus Genetics Citizens JmpSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageMarket Perform$12.004/21/2026IRDOpus Genetics Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingSell (D-)4/21/2026PBYIPuma Biotechnology Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingHold (C+)4/21/2026SRZNSurrozen Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingSell (D-)4/21/2026SRZNSurrozen TD CowenSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageBuy(Data available from 5/15/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookIRDOpus Genetics$14.20M28.49N/AN/A($0.56) per share-8.88PBYIPuma Biotechnology$228.40M1.60$0.84 per share8.59$2.52 per share2.85PMNPromis NeurosciencesN/AN/AN/AN/A$6.77 per shareN/ASRZNSurrozen$3.48M99.65N/AN/A($23.96) per share-1.25Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateIRDOpus Genetics-$49.59M-$1.33N/AN/AN/A-892.36%-709.20%-191.21%5/21/2026 (Estimated)PBYIPuma Biotechnology$31.11M$0.4814.9837.84N/A10.69%20.30%12.05%N/APMNPromis Neurosciences-$39.72M-$19.00N/AN/AN/AN/A-237.99%-151.04%N/ASRZNSurrozen-$242.03M-$37.59N/AN/AN/A-4,810.50%-4,055.04%-154.08%N/ALatest PMN, PBYI, IRD, and SRZN EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/21/2026Q1 2026IRDOpus Genetics-$0.16N/AN/AN/A$3.14 millionN/A5/12/2026Q1 2026IRDOpus Genetics-$0.16-$0.75-$0.59-$0.75$2.93 million$2.16 million5/12/2026Q1 2026PMNPromis Neurosciences-$1.06-$1.26-$0.20-$1.26N/AN/A5/7/2026Q1 2026PBYIPuma Biotechnology-$0.13-$0.04+$0.09-$0.07$42.00 million$44.81 million5/6/2026Q1 2026SRZNSurrozen-$1.0920-$11.65-$10.5580-$11.65$4.00 million$5.00 million3/23/2026Q4 2025SRZNSurrozen-$1.2875-$7.59-$6.3025-$23.88$0.66 million$0.53 million2/26/2026Q4 2025PBYIPuma Biotechnology$0.24$0.26+$0.02$0.26$68.60 million$75.50 millionCompare DividendsCompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive GrowthIRDOpus GeneticsN/AN/AN/AN/AN/APBYIPuma BiotechnologyN/AN/AN/AN/AN/APMNPromis NeurosciencesN/AN/AN/AN/AN/ASRZNSurrozenN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioIRDOpus GeneticsN/A7.136.43PBYIPuma BiotechnologyN/A2.381.93PMNPromis NeurosciencesN/A9.920.88SRZNSurrozenN/A11.9111.91Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipIRDOpus Genetics14.97%PBYIPuma Biotechnology61.29%PMNPromis Neurosciences50.13%SRZNSurrozen66.57%Insider OwnershipCompanyInsider OwnershipIRDOpus Genetics11.70%PBYIPuma Biotechnology22.20%PMNPromis Neurosciences1.50%SRZNSurrozen31.74%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableIRDOpus Genetics1481.40 million63.05 millionN/APBYIPuma Biotechnology20050.90 million39.60 millionOptionablePMNPromis Neurosciences58.97 million8.83 millionNot OptionableSRZNSurrozen8011.61 million7.84 millionNot OptionablePMN, PBYI, IRD, and SRZN HeadlinesRecent News About These CompaniesSurrozen (SRZN) price target increased by 10.11% to 43.52May 14 at 11:25 PM | msn.comSurrozen Shareholders Support Board, Auditor and Pay PoliciesMay 14 at 4:50 PM | tipranks.comSurrozen to Present at Upcoming Healthcare Investor ConferenceMay 12 at 4:05 PM | globenewswire.comHC Wainwright Estimates Surrozen's Q2 Earnings (NASDAQ:SRZN)May 11, 2026 | marketbeat.comLifesci Capital Has Strong Forecast for Surrozen Q2 EarningsMay 11, 2026 | marketbeat.comRigel Pharmaceuticals (NASDAQ:RIGL) versus Surrozen (NASDAQ:SRZN) Head to Head ComparisonMay 10, 2026 | americanbankingnews.comWhat is Lifesci Capital's Forecast for Surrozen Q1 Earnings?May 8, 2026 | marketbeat.comSurrozen (NASDAQ:SRZN) Releases Earnings Results, Misses Estimates By $10.56 EPSMay 6, 2026 | marketbeat.comSurrozen Reports First Quarter 2026 Financial Results and Provides Business UpdateMay 6, 2026 | globenewswire.comInsider Selling: Surrozen (NASDAQ:SRZN) VP Sells 1,584 Shares of StockMay 6, 2026 | insidertrades.comYang Li Sells 1,584 Shares of Surrozen (NASDAQ:SRZN) StockMay 5, 2026 | marketbeat.comSurrozen (NASDAQ:SRZN) COO Charles Williams Sells 2,036 SharesMay 5, 2026 | marketbeat.comSurrozen (NASDAQ:SRZN) CEO Craig Parker Sells 4,524 SharesMay 5, 2026 | marketbeat.comSurrozen (SRZN) Projected to Post Quarterly Earnings on FridayMay 1, 2026 | marketbeat.comSurrozen, Inc. (NASDAQ:SRZN) Sees Large Growth in Short InterestApril 29, 2026 | marketbeat.comSurrozen Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)April 28, 2026 | globenewswire.comTD Cowen initiates coverage of Surrozen (SRZN) with buy recommendationApril 23, 2026 | msn.comSurrozen, Inc. (NASDAQ:SRZN) Receives Average Rating of "Moderate Buy" from BrokeragesApril 21, 2026 | marketbeat.comSurrozen (SRZN) Surges 5.9%: Is This an Indication of Further Gains?April 14, 2026 | zacks.comLifeSci Capital Keeps Their Buy Rating on Surrozen (SRZN)March 29, 2026 | theglobeandmail.comSurrozen (NASDAQ:SRZN) Major Shareholder Tcg Crossover Gp Ii, Llc Purchases 15,223 SharesMarch 26, 2026 | insidertrades.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesThe Real SpaceX Play: 5 Chip Stocks Powering the IPO Before It LaunchesBy Bridget Bennett | May 4, 2026Allbirds Exits Shoes, Pivots to AI With NewBird RebrandBy Leo Miller | April 21, 2026AST SpaceMobile Drops 15% After Blue Origin Satellite MishapBy Jessica Mitacek | April 22, 2026AST SpaceMobile Gets FCC Green Light for Direct-to-Device Service After Launch SetbackBy Jessica Mitacek | April 28, 2026AST SpaceMobile Plummets on Galactic Q1 Miss: Can Vertical Integration Save the SpaceX Rival?By Jessica Mitacek | May 12, 2026PMN, PBYI, IRD, and SRZN Company DescriptionsOpus Genetics NASDAQ:IRD$4.97 -0.06 (-1.19%) Closing price 05/14/2026 04:00 PM EasternExtended Trading$5.04 +0.07 (+1.31%) As of 04:14 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Opus Genetics Inc. is a clinical-stage ophthalmic biopharmaceutical company, focuses on developing and commercializing therapies for the treatment of unmet needs of patients with refractive and retinal eye disorders. Opus Genetics Inc., formerly known as Ocuphire Pharma Inc., is based in Farmington Hills, Michigan.Puma Biotechnology NASDAQ:PBYI$7.19 +0.02 (+0.28%) Closing price 05/14/2026 04:00 PM EasternExtended Trading$7.20 +0.00 (+0.07%) As of 05/14/2026 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. The company offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. It also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. The company sells its products through specialty pharmacy and distributor networks. It has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds; and Takeda Pharmaceutical Company Limited for the research, development, and commercialization of alisertib, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. The company was founded in 2010 and is headquartered in Los Angeles, California.Promis Neurosciences NASDAQ:PMN$10.58 +0.01 (+0.09%) Closing price 05/14/2026 04:00 PM EasternExtended Trading$10.30 -0.28 (-2.64%) As of 04:05 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.ProMIS Neurosciences, Inc. discovers and develops antibody therapies and therapeutic vaccines neurodegenerative diseases and other misfolded protein diseases in Canada. The company's proprietary discovery platform comprises ProMIS and Collective Coordinates algorithms to predict novel targets known as disease specific epitopes on the molecular surface of misfolded proteins. Its lead product candidates comprise of PMN310, a monoclonal antibody (mAb) for toxic oligomers in AD; PMN267, a TDP-43; and PMN442, a mAb targeting toxic a-syn oligomers and seeding fibrils. The company was formerly known as Amorfix Life Sciences Ltd. and changed its name to ProMIS Neurosciences, Inc. in July 2015. ProMIS Neurosciences, Inc. was incorporated in 2004 and is headquartered in Toronto, Canada.Surrozen NASDAQ:SRZN$29.87 -0.27 (-0.90%) Closing price 05/14/2026 04:00 PM EasternExtended Trading$29.19 -0.68 (-2.27%) As of 04:00 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Surrozen, Inc., a clinical stage biotechnology company, discovers and develops drug candidates to selectively modulate the Wnt pathway for tissue repair. The company is developing antibody-based therapeutics which targets various disease areas, including diseases of the intestine, liver, retina, cornea, lung, kidney, cochlea, skin, pancreas, and central nervous system. Its products in pipeline include SZN-043, a hepatocyte-specific R-spondin mimetic bispecific fusion protein, which is in Phase 1b clinical trial for the treatment of severe liver diseases, including alcohol-associated hepatitis. The company develops SZN-413, a Fzd4 targeted bi-specific antibody for the treatment of retinal vascular associated diseases. Surrozen, Inc. has collaboration and license agreement with Boehringer Ingelheim International GmbH to research, develop, and commercialize Fzd4 bi-specific antibodies. Surrozen, Inc. is based in South San Francisco, California. 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