| 4/30/2026 | Hsbc Holdings PLC | 122,834 | $640K | 0.0% | -28.9% | 0.260% | |
| 4/16/2026 | SG Americas Securities LLC | 286,698 | $1.51M | 0.0% | +11.8% | 0.607% | |
| 2/26/2026 | Seven Fleet Capital Management LP | 147,600 | $897K | 0.7% | N/A | 0.313% | |
| 2/18/2026 | XTX Topco Ltd | 11,718 | $71K | 0.0% | N/A | 0.025% | |
| 2/18/2026 | Ikarian Capital LLC | 865,784 | $5.26M | 0.4% | -3.9% | 1.833% | |
| 2/18/2026 | Quadrature Capital Ltd | 54,380 | $331K | 0.0% | N/A | 0.115% | |
| 2/18/2026 | Opaleye Management Inc. | 78,926 | $480K | 0.1% | N/A | 0.167% | |
| 2/18/2026 | Millennium Management LLC | 659,592 | $4.01M | 0.0% | +121.0% | 1.397% | |
| 2/18/2026 | Ishara Investments LP | 240,000 | $1.46M | 1.7% | N/A | 0.508% | |
| 2/18/2026 | Boothbay Fund Management LLC | 209,088 | $1.27M | 0.0% | -25.2% | 0.443% | |
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| 2/17/2026 | ADAR1 Capital Management LLC | 23,643 | $144K | 0.0% | +26.8% | 0.050% | |
| 2/17/2026 | Lombard Odier Asset Management USA Corp | 255,901 | $1.56M | 0.1% | -86.1% | 0.542% | |
| 2/13/2026 | Nantahala Capital Management LLC | 1,542,427 | $9.38M | 0.3% | +48.0% | 3.266% | |
| 2/13/2026 | Marshall Wace LLP | 155,680 | $947K | 0.0% | +87.1% | 0.330% | |
| 2/12/2026 | Jane Street Group LLC | 29,168 | $177K | 0.0% | N/A | 0.062% | |
| 2/12/2026 | Bank of Montreal Can | 160,474 | $976K | 0.0% | +4.4% | 0.340% | |
| 2/10/2026 | Goldman Sachs Group Inc. | 18,114 | $110K | 0.0% | -20.0% | 0.038% | |
| 1/29/2026 | China Universal Asset Management Co. Ltd. | 13,653 | $83K | 0.0% | +65.9% | 0.029% | |
| 1/9/2026 | SG Americas Securities LLC | 256,340 | $1.56M | 0.0% | -16.9% | 0.543% | |
| 12/1/2025 | Cantor Fitzgerald L. P. | 801,306 | $4.16M | 0.0% | +1.6% | 1.697% | |
| 11/17/2025 | Wexford Capital LP | 7,708 | $40K | 0.0% | -71.6% | 0.016% | |
| 11/17/2025 | Lombard Odier Asset Management USA Corp | 1,844,948 | $9.58M | 0.6% | -0.3% | 3.906% | |
| 11/17/2025 | Millennium Management LLC | 298,512 | $1.55M | 0.0% | +50.3% | 0.632% | |
| 11/17/2025 | Citadel Advisors LLC | 21,505 | $112K | 0.0% | N/A | 0.046% | |
| 11/17/2025 | Cantor Fitzgerald L. P. | 801,306 | $4.16M | 0.0% | +1.6% | 1.697% | |
| 11/17/2025 | Boothbay Fund Management LLC | 279,637 | $1.45M | 0.0% | +10.8% | 0.592% | |
| 11/14/2025 | Two Sigma Investments LP | 63,247 | $328K | 0.0% | +6.6% | 0.000% | |
| 11/14/2025 | EHP Funds Inc. | 10,673 | $55K | 0.0% | N/A | 0.000% | |
| 11/13/2025 | UBS Group AG | 307,363 | $1.60M | 0.0% | +34.5% | 1.027% | |
| 9/4/2025 | Osaic Holdings Inc. | 69,381 | $402K | 0.0% | -3.0% | 0.232% | |
| 8/15/2025 | Massar Capital Management LP | 19,863 | $115K | 0.1% | N/A | 0.000% | |
| 8/15/2025 | Frazier Life Sciences Management L.P. | 970,130 | $5.63M | 0.2% | -15.5% | 0.000% | |
| 8/15/2025 | Boothbay Fund Management LLC | 252,421 | $1.46M | 0.0% | +1.0% | 0.000% | |
| 8/15/2025 | Bank of America Corp DE | 5,095 | $30K | 0.0% | -92.1% | 0.000% | |
| 8/14/2025 | Redmile Group LLC | 2,164,777 | $12.56M | 1.3% | -2.3% | 7.233% | |
| 8/13/2025 | Marshall Wace LLP | 175,862 | $1.02M | 0.0% | -23.0% | 0.000% | |
| 8/13/2025 | Saturn V Capital Management LP | 34,737 | $201K | 0.1% | -95.3% | 0.000% | |
| 8/13/2025 | Beacon Pointe Advisors LLC | 11,615 | $67K | 0.0% | N/A | 0.000% | |
| 8/13/2025 | Virtus Investment Advisers LLC | 16,837 | $98K | 0.0% | -32.3% | 0.000% | |
| 8/12/2025 | Evelyn Partners Investment Management Services Ltd | 14,334 | $77K | 0.0% | +481.3% | 0.000% | |
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| 8/12/2025 | JPMorgan Chase & Co. | 7,283 | $42K | 0.0% | -79.4% | 0.000% | |
| 8/5/2025 | Bank of Montreal Can | 145,812 | $846K | 0.0% | -8.1% | 0.000% | |
| 7/14/2025 | GAMMA Investing LLC | 8,333 | $48K | 0.0% | +134.1% | 0.000% | |
| 6/27/2025 | Goldman Sachs Group Inc. | 24,375 | $69K | 0.0% | -33.9% | 0.000% | |
| 5/23/2025 | Siren L.L.C. | 2,789,833 | $7.87M | 0.5% | -1.5% | 9.321% | |
| 5/21/2025 | Acadian Asset Management LLC | 12,153 | $34K | 0.0% | -37.6% | 0.041% | |
| 5/16/2025 | Woodline Partners LP | 134,492 | $379K | 0.0% | -73.0% | 0.449% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 24,375 | $69K | 0.0% | -33.9% | 0.081% | |
| 5/16/2025 | Parkman Healthcare Partners LLC | 401,746 | $1.13M | 0.1% | -18.2% | 1.342% | |
| 5/15/2025 | Redmile Group LLC | 2,214,947 | $6.25M | 0.6% | -7.7% | 7.400% | |
| 5/15/2025 | Nantahala Capital Management LLC | 1,042,427 | $2.94M | 0.1% | -0.7% | 3.483% | |
| 5/15/2025 | Siren L.L.C. | 2,789,833 | $7.87M | 0.5% | -1.5% | 9.321% | |
| 5/14/2025 | Walleye Capital LLC | 136,150 | $384K | 0.0% | +274.1% | 0.455% | |
| 5/14/2025 | Jump Financial LLC | 26,351 | $74K | 0.0% | N/A | 0.088% | |
| 4/15/2025 | SG Americas Securities LLC | 308,289 | $869K | 0.0% | -2.9% | 1.030% | |
| 2/17/2025 | Woodline Partners LP | 498,732 | $3.43M | 0.0% | +22.6% | 1.666% | |
| 2/17/2025 | Two Sigma Advisers LP | 98,800 | $680K | 0.0% | +18.6% | 0.330% | |
| 2/17/2025 | Two Sigma Investments LP | 142,052 | $977K | 0.0% | -16.1% | 0.475% | |
| 2/17/2025 | Redmile Group LLC | 2,399,317 | $16.51M | 1.2% | +26.3% | 8.016% | |
| 2/17/2025 | Point72 Asset Management L.P. | 633,100 | $4.36M | 0.0% | +35.3% | 2.115% | |
| 2/17/2025 | Parkman Healthcare Partners LLC | 491,080 | $3.38M | 0.4% | -1.4% | 1.641% | |
| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 128,990 | $887K | 0.1% | +50.5% | 0.431% | |
| 2/17/2025 | Millennium Management LLC | 473,552 | $3.26M | 0.0% | -57.3% | 1.582% | |
| 2/17/2025 | Integral Health Asset Management LLC | 200,000 | $1.38M | 0.1% | N/A | 0.668% | |
| 2/17/2025 | Cubist Systematic Strategies LLC | 106,320 | $731K | 0.0% | +129.6% | 0.355% | |
| 2/17/2025 | Cantor Fitzgerald L. P. | 539,726 | $3.71M | 0.1% | +61.5% | 1.803% | |
| 2/17/2025 | Bank of America Corp DE | 499,066 | $3.43M | 0.0% | +48,165.6% | 1.667% | |
| 2/17/2025 | Ameriprise Financial Inc. | 16,360 | $113K | 0.0% | N/A | 0.055% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 123,200 | $848K | 0.0% | -25.8% | 0.412% | |
| 2/14/2025 | Nantahala Capital Management LLC | 1,049,676 | $7.22M | 0.3% | +424.8% | 3.507% | |
| 2/14/2025 | Boothbay Fund Management LLC | 351,527 | $2.42M | 0.1% | +105.4% | 1.174% | |
| 2/14/2025 | Virtus ETF Advisers LLC | 10,772 | $74K | 0.0% | +130.5% | 0.036% | |
| 2/14/2025 | Hsbc Holdings PLC | 172,834 | $1.19M | 0.0% | -2.8% | 0.577% | |
| 2/13/2025 | Marshall Wace LLP | 488,889 | $3.36M | 0.0% | +190.3% | 1.633% | |
| 2/13/2025 | Walleye Capital LLC | 36,397 | $250K | 0.0% | N/A | 0.122% | |
| 2/13/2025 | Barclays PLC | 6,126 | $42K | 0.0% | +83.8% | 0.020% | |
| 2/13/2025 | ADAR1 Capital Management LLC | 18,000 | $124K | 0.0% | -55.3% | 0.060% | |
| 2/12/2025 | Trexquant Investment LP | 63,663 | $438K | 0.0% | N/A | 0.213% | |
| 2/12/2025 | JPMorgan Chase & Co. | 3,793 | $26K | 0.0% | N/A | 0.013% | |
| 2/11/2025 | Commonwealth of Pennsylvania Public School Empls Retrmt SYS | 19,467 | $134K | 0.0% | N/A | 0.065% | |
| 1/24/2025 | China Universal Asset Management Co. Ltd. | 9,963 | $69K | 0.0% | N/A | 0.033% | |
| 1/23/2025 | Custom Index Systems LLC | 11,861 | $82K | 0.0% | -17.7% | 0.040% | |
| 1/17/2025 | SG Americas Securities LLC | 317,628 | $2.19M | 0.0% | -7.4% | 1.061% | |
| 1/13/2025 | FNY Investment Advisers LLC | 17,515 | $120K | 0.1% | N/A | 0.059% | |
| 1/3/2025 | GAMMA Investing LLC | 6,092 | $42K | 0.0% | +609.2% | 0.020% | |
| 11/19/2024 | Barclays PLC | 3,333 | $61K | 0.0% | -40.2% | 0.011% | |
| 11/15/2024 | Barclays PLC | 3,333 | $61K | 0.0% | -40.2% | 0.011% | |
| 11/15/2024 | Y Intercept Hong Kong Ltd | 21,078 | $383K | 0.0% | +22.9% | 0.070% | |
| 11/15/2024 | Redmile Group LLC | 1,899,317 | $34.53M | 2.0% | -5.7% | 6.346% | |
| 11/15/2024 | Point72 Asset Management L.P. | 467,800 | $8.51M | 0.0% | +219.3% | 1.563% | |
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| 11/15/2024 | Parkman Healthcare Partners LLC | 497,870 | $9.05M | 1.2% | +71.8% | 1.664% | |
| 11/15/2024 | Ikarian Capital LLC | 587,343 | $10.68M | 1.4% | +15.9% | 1.962% | |
| 11/15/2024 | Janus Henderson Group PLC | 1,087,228 | $19.80M | 0.0% | +32.8% | 3.633% | |
| 11/14/2024 | Eventide Asset Management LLC | 640,000 | $11.64M | 0.2% | N/A | 2.138% | |
| 11/14/2024 | Verition Fund Management LLC | 11,390 | $207K | 0.0% | N/A | 0.038% | |
| 11/13/2024 | The Manufacturers Life Insurance Company | 17,490 | $318K | 0.0% | N/A | 0.058% | |
| 10/23/2024 | Values First Advisors Inc. | 3,091 | $56K | 0.0% | N/A | 0.010% | |
| 9/16/2024 | Cubist Systematic Strategies LLC | 9,438 | $179K | 0.0% | -74.0% | 0.032% | |
| 8/19/2024 | Point72 Asset Management L.P. | 146,500 | $2.78M | 0.0% | +1,686.6% | 0.490% | |
| 8/16/2024 | Quarry LP | 6,000 | $114K | 0.0% | N/A | 0.020% | |