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Silence Therapeutics (SLN) Competitors

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$11.28 +0.60 (+5.62%)
As of 11:43 AM Eastern
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SLN vs. AMLX, KLRA, AGIO, ZLAB, and SION

Should you buy Silence Therapeutics stock or one of its competitors? MarketBeat compares Silence Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Silence Therapeutics include Amylyx Pharmaceuticals (AMLX), Kailera Therapeutics (KLRA), Agios Pharmaceuticals (AGIO), Zai Lab (ZLAB), and Sionna Therapeutics (SION).

How does Silence Therapeutics compare to Amylyx Pharmaceuticals?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and Silence Therapeutics (NASDAQ:SLN) are both healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their risk, media sentiment, dividends, institutional ownership, earnings, analyst recommendations, profitability and valuation.

Silence Therapeutics has lower revenue, but higher earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx Pharmaceuticals$87.37M27.52-$144.74M-$1.50N/A
Silence Therapeutics$560K951.55-$88.61M-$1.59N/A

In the previous week, Amylyx Pharmaceuticals had 4 more articles in the media than Silence Therapeutics. MarketBeat recorded 7 mentions for Amylyx Pharmaceuticals and 3 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 1.00 beat Amylyx Pharmaceuticals' score of 0.95 indicating that Silence Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
3 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Amylyx Pharmaceuticals currently has a consensus price target of $25.38, suggesting a potential upside of 17.35%. Silence Therapeutics has a consensus price target of $55.00, suggesting a potential upside of 387.59%. Given Silence Therapeutics' higher probable upside, analysts clearly believe Silence Therapeutics is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. Comparatively, 98.7% of Silence Therapeutics shares are held by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are held by company insiders. Comparatively, 3.0% of Silence Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Amylyx Pharmaceuticals' return on equity of -55.69% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -55.69% -50.73%
Silence Therapeutics -8,943.86%-105.34%-52.79%

Amylyx Pharmaceuticals has a beta of -0.21, meaning that its share price is 121% less volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.39, meaning that its share price is 39% more volatile than the broader market.

Summary

Amylyx Pharmaceuticals beats Silence Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Silence Therapeutics compare to Kailera Therapeutics?

Silence Therapeutics (NASDAQ:SLN) and Kailera Therapeutics (NASDAQ:KLRA) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their profitability, institutional ownership, analyst recommendations, risk, media sentiment, dividends, earnings and valuation.

98.7% of Silence Therapeutics shares are held by institutional investors. 3.0% of Silence Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

In the previous week, Silence Therapeutics and Silence Therapeutics both had 3 articles in the media. Silence Therapeutics' average media sentiment score of 1.00 beat Kailera Therapeutics' score of -0.33 indicating that Silence Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Kailera Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Kailera Therapeutics has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Kailera Therapeutics' return on equity of 0.00% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Silence Therapeutics-8,943.86% -105.34% -52.79%
Kailera Therapeutics N/A N/A N/A

Silence Therapeutics currently has a consensus target price of $55.00, suggesting a potential upside of 387.59%. Kailera Therapeutics has a consensus target price of $42.75, suggesting a potential upside of 141.53%. Given Silence Therapeutics' higher probable upside, research analysts plainly believe Silence Therapeutics is more favorable than Kailera Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Kailera Therapeutics
0 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
3.00

Kailera Therapeutics has lower revenue, but higher earnings than Silence Therapeutics. Silence Therapeutics is trading at a lower price-to-earnings ratio than Kailera Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Silence Therapeutics$560K951.55-$88.61M-$1.59N/A
Kailera TherapeuticsN/AN/AN/A-$3.65 thousandN/A

Summary

Silence Therapeutics and Kailera Therapeutics tied by winning 6 of the 12 factors compared between the two stocks.

How does Silence Therapeutics compare to Agios Pharmaceuticals?

Silence Therapeutics (NASDAQ:SLN) and Agios Pharmaceuticals (NASDAQ:AGIO) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, dividends, analyst recommendations, valuation, institutional ownership, earnings, profitability and risk.

Agios Pharmaceuticals has a net margin of -418.24% compared to Silence Therapeutics' net margin of -8,943.86%. Agios Pharmaceuticals' return on equity of -35.67% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Silence Therapeutics-8,943.86% -105.34% -52.79%
Agios Pharmaceuticals -418.24%-35.67%-33.06%

Silence Therapeutics has a beta of 1.39, suggesting that its share price is 39% more volatile than the broader market. Comparatively, Agios Pharmaceuticals has a beta of 0.54, suggesting that its share price is 46% less volatile than the broader market.

Silence Therapeutics currently has a consensus target price of $55.00, indicating a potential upside of 387.59%. Agios Pharmaceuticals has a consensus target price of $40.88, indicating a potential upside of 32.03%. Given Silence Therapeutics' stronger consensus rating and higher possible upside, equities analysts plainly believe Silence Therapeutics is more favorable than Agios Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Agios Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.40

Silence Therapeutics has higher earnings, but lower revenue than Agios Pharmaceuticals. Silence Therapeutics is trading at a lower price-to-earnings ratio than Agios Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Silence Therapeutics$560K951.55-$88.61M-$1.59N/A
Agios Pharmaceuticals$98.34M18.72-$412.78M-$7.01N/A

In the previous week, Agios Pharmaceuticals had 27 more articles in the media than Silence Therapeutics. MarketBeat recorded 30 mentions for Agios Pharmaceuticals and 3 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 1.00 beat Agios Pharmaceuticals' score of 0.41 indicating that Silence Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Agios Pharmaceuticals
8 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
3 Negative mention(s)
2 Very Negative mention(s)
Neutral

98.7% of Silence Therapeutics shares are held by institutional investors. 3.0% of Silence Therapeutics shares are held by insiders. Comparatively, 5.4% of Agios Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Summary

Silence Therapeutics beats Agios Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Silence Therapeutics compare to Zai Lab?

Zai Lab (NASDAQ:ZLAB) and Silence Therapeutics (NASDAQ:SLN) are both healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their profitability, dividends, risk, earnings, analyst recommendations, valuation, media sentiment and institutional ownership.

Silence Therapeutics has lower revenue, but higher earnings than Zai Lab. Zai Lab is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zai Lab$460.16M4.54-$175.54M-$1.62N/A
Silence Therapeutics$560K951.55-$88.61M-$1.59N/A

In the previous week, Zai Lab had 2 more articles in the media than Silence Therapeutics. MarketBeat recorded 5 mentions for Zai Lab and 3 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 1.00 beat Zai Lab's score of 0.11 indicating that Silence Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zai Lab
0 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

41.7% of Zai Lab shares are held by institutional investors. Comparatively, 98.7% of Silence Therapeutics shares are held by institutional investors. 4.9% of Zai Lab shares are held by insiders. Comparatively, 3.0% of Silence Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Zai Lab has a net margin of -39.29% compared to Silence Therapeutics' net margin of -8,943.86%. Zai Lab's return on equity of -24.32% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Zai Lab-39.29% -24.32% -15.52%
Silence Therapeutics -8,943.86%-105.34%-52.79%

Zai Lab currently has a consensus target price of $40.00, indicating a potential upside of 117.85%. Silence Therapeutics has a consensus target price of $55.00, indicating a potential upside of 387.59%. Given Silence Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Silence Therapeutics is more favorable than Zai Lab.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zai Lab
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

Zai Lab has a beta of 0.78, meaning that its stock price is 22% less volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.39, meaning that its stock price is 39% more volatile than the broader market.

Summary

Silence Therapeutics beats Zai Lab on 9 of the 15 factors compared between the two stocks.

How does Silence Therapeutics compare to Sionna Therapeutics?

Silence Therapeutics (NASDAQ:SLN) and Sionna Therapeutics (NASDAQ:SION) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, profitability, risk, dividends, institutional ownership, earnings, valuation and analyst recommendations.

Silence Therapeutics presently has a consensus price target of $55.00, suggesting a potential upside of 387.59%. Sionna Therapeutics has a consensus price target of $53.22, suggesting a potential upside of 5.07%. Given Silence Therapeutics' higher probable upside, research analysts clearly believe Silence Therapeutics is more favorable than Sionna Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85

98.7% of Silence Therapeutics shares are held by institutional investors. 3.0% of Silence Therapeutics shares are held by insiders. Comparatively, 5.1% of Sionna Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Sionna Therapeutics has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Sionna Therapeutics' return on equity of -27.31% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Silence Therapeutics-8,943.86% -105.34% -52.79%
Sionna Therapeutics N/A -27.31%-25.88%

Silence Therapeutics has a beta of 1.39, suggesting that its share price is 39% more volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 1.32, suggesting that its share price is 32% more volatile than the broader market.

In the previous week, Silence Therapeutics and Silence Therapeutics both had 3 articles in the media. Sionna Therapeutics' average media sentiment score of 1.22 beat Silence Therapeutics' score of 1.00 indicating that Sionna Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Sionna Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Sionna Therapeutics has lower revenue, but higher earnings than Silence Therapeutics. Sionna Therapeutics is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Silence Therapeutics$560K951.55-$88.61M-$1.59N/A
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A

Summary

Sionna Therapeutics beats Silence Therapeutics on 9 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SLN and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SLN vs. The Competition

MetricSilence TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$532.02M$3.53B$6.80B$12.89B
Dividend YieldN/A3.79%2.60%10.03%
P/E Ratio-7.087.33279.9025.40
Price / Sales951.551,274.10648.58114.39
Price / CashN/A44.8028.6434.82
Price / Book8.5517.1211.106.30
Net Income-$88.61M-$12.52M$3.48B$347.60M
7 Day Performance-2.34%1.54%1.93%2.53%
1 Month Performance8.57%-6.32%-3.29%-2.57%
1 Year Performance89.58%49.25%62.38%20.26%

Silence Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SLN
Silence Therapeutics
3.4705 of 5 stars
$11.28
+5.6%
$55.00
+387.6%
+73.1%$532.02M$560KN/A100
AMLX
Amylyx Pharmaceuticals
4.0282 of 5 stars
$19.55
+0.3%
$24.63
+26.0%
+161.3%$2.17B$87.37MN/A200
KLRA
Kailera Therapeutics
2.9085 of 5 stars
$16.74
-4.2%
$42.75
+155.4%
N/A$2.17BN/AN/A145
AGIO
Agios Pharmaceuticals
2.8029 of 5 stars
$35.99
-2.7%
$40.00
+11.1%
-12.7%$2.14B$54.03MN/A390
ZLAB
Zai Lab
3.3921 of 5 stars
$18.62
-0.1%
$40.00
+114.8%
-50.6%$2.12B$460.16MN/A1,784

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This page (NASDAQ:SLN) was last updated on 8/4/2026 by MarketBeat.com Staff.
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