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Silence Therapeutics (SLN) Competitors

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$10.64 -0.07 (-0.65%)
Closing price 10/2/2026 04:00 PM Eastern
Extended Trading
$10.66 +0.01 (+0.14%)
As of 10/2/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

SLN vs. BEAM, IRON, IMNM, CLDX, and NRIX

Should you buy Silence Therapeutics stock or one of its competitors? Silence Therapeutics's main competitors and comparable companies include Beam Therapeutics (BEAM), Disc Medicine (IRON), Immunome (IMNM), Celldex Therapeutics (CLDX), and Nurix Therapeutics (NRIX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Silence Therapeutics compare to Beam Therapeutics?

Silence Therapeutics (NASDAQ:SLN) and Beam Therapeutics (NASDAQ:BEAM) are both healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their media sentiment, valuation, profitability, dividends, analyst recommendations, risk, earnings and institutional ownership.

Silence Therapeutics has a beta of 1.45, suggesting that its share price is 45% more volatile than the broader market. Comparatively, Beam Therapeutics has a beta of 2.2, suggesting that its share price is 120% more volatile than the broader market.

Beam Therapeutics has a net margin of -54.75% compared to Silence Therapeutics' net margin of -8,943.86%. Beam Therapeutics' return on equity of -30.71% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Silence Therapeutics-8,943.86% -106.94% -47.99%
Beam Therapeutics -54.75%-30.71%-24.07%

In the previous week, Beam Therapeutics had 5 more articles in the media than Silence Therapeutics. MarketBeat recorded 6 mentions for Beam Therapeutics and 1 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 0.78 beat Beam Therapeutics' score of 0.23 indicating that Silence Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Silence Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Beam Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Silence Therapeutics currently has a consensus price target of $53.50, suggesting a potential upside of 402.82%. Beam Therapeutics has a consensus price target of $49.00, suggesting a potential upside of 100.00%. Given Silence Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Silence Therapeutics is more favorable than Beam Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Beam Therapeutics
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.79

98.7% of Silence Therapeutics shares are held by institutional investors. Comparatively, 99.7% of Beam Therapeutics shares are held by institutional investors. 3.0% of Silence Therapeutics shares are held by insiders. Comparatively, 3.8% of Beam Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Beam Therapeutics has higher revenue and earnings than Silence Therapeutics. Beam Therapeutics is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Silence Therapeutics$560K1,143.99-$88.61M-$1.28N/A
Beam Therapeutics$139.74M18.11-$79.99M-$0.86N/A

Summary

Beam Therapeutics beats Silence Therapeutics on 11 of the 16 factors compared between the two stocks.

How does Silence Therapeutics compare to Disc Medicine?

Silence Therapeutics (NASDAQ:SLN) and Disc Medicine (NASDAQ:IRON) are both small-cap healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their profitability, valuation, analyst recommendations, risk, media sentiment, earnings, dividends and institutional ownership.

In the previous week, Disc Medicine had 4 more articles in the media than Silence Therapeutics. MarketBeat recorded 5 mentions for Disc Medicine and 1 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 0.78 beat Disc Medicine's score of 0.41 indicating that Silence Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Silence Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Disc Medicine
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Disc Medicine has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Disc Medicine's return on equity of -37.17% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Silence Therapeutics-8,943.86% -106.94% -47.99%
Disc Medicine N/A -37.17%-33.65%

Silence Therapeutics has a beta of 1.45, suggesting that its share price is 45% more volatile than the broader market. Comparatively, Disc Medicine has a beta of 0.93, suggesting that its share price is 7% less volatile than the broader market.

98.7% of Silence Therapeutics shares are held by institutional investors. Comparatively, 83.7% of Disc Medicine shares are held by institutional investors. 3.0% of Silence Therapeutics shares are held by company insiders. Comparatively, 3.8% of Disc Medicine shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Silence Therapeutics has higher revenue and earnings than Disc Medicine. Disc Medicine is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Silence Therapeutics$560K1,143.99-$88.61M-$1.28N/A
Disc MedicineN/AN/A-$212.18M-$6.58N/A

Silence Therapeutics presently has a consensus target price of $53.50, suggesting a potential upside of 402.82%. Disc Medicine has a consensus target price of $110.18, suggesting a potential upside of 70.80%. Given Silence Therapeutics' stronger consensus rating and higher probable upside, equities analysts plainly believe Silence Therapeutics is more favorable than Disc Medicine.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Disc Medicine
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

Summary

Silence Therapeutics beats Disc Medicine on 10 of the 16 factors compared between the two stocks.

How does Silence Therapeutics compare to Immunome?

Immunome (NASDAQ:IMNM) and Silence Therapeutics (NASDAQ:SLN) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their dividends, risk, valuation, earnings, institutional ownership, analyst recommendations, profitability and media sentiment.

Immunome has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Immunome's return on equity of -50.56% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunomeN/A -50.56% -46.93%
Silence Therapeutics -8,943.86%-106.94%-47.99%

44.6% of Immunome shares are held by institutional investors. Comparatively, 98.7% of Silence Therapeutics shares are held by institutional investors. 7.2% of Immunome shares are held by company insiders. Comparatively, 3.0% of Silence Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Immunome has a beta of 2.55, meaning that its stock price is 155% more volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.45, meaning that its stock price is 45% more volatile than the broader market.

Silence Therapeutics has lower revenue, but higher earnings than Immunome. Silence Therapeutics is trading at a lower price-to-earnings ratio than Immunome, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Immunome$6.94M342.05-$212.39M-$2.53N/A
Silence Therapeutics$560K1,143.99-$88.61M-$1.28N/A

Immunome currently has a consensus target price of $34.25, suggesting a potential upside of 63.88%. Silence Therapeutics has a consensus target price of $53.50, suggesting a potential upside of 402.82%. Given Silence Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Silence Therapeutics is more favorable than Immunome.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immunome
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
0 Strong Buy rating(s)
2.79
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

In the previous week, Immunome had 10 more articles in the media than Silence Therapeutics. MarketBeat recorded 11 mentions for Immunome and 1 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 0.78 beat Immunome's score of 0.62 indicating that Silence Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Immunome
3 Very Positive mention(s)
5 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Silence Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Immunome beats Silence Therapeutics on 9 of the 17 factors compared between the two stocks.

How does Silence Therapeutics compare to Celldex Therapeutics?

Celldex Therapeutics (NASDAQ:CLDX) and Silence Therapeutics (NASDAQ:SLN) are both healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, earnings, valuation, media sentiment, risk, analyst recommendations, profitability and institutional ownership.

In the previous week, Celldex Therapeutics had 2 more articles in the media than Silence Therapeutics. MarketBeat recorded 3 mentions for Celldex Therapeutics and 1 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 0.78 beat Celldex Therapeutics' score of 0.18 indicating that Silence Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Celldex Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Silence Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Celldex Therapeutics has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Celldex Therapeutics' return on equity of -52.35% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Celldex TherapeuticsN/A -52.35% -47.61%
Silence Therapeutics -8,943.86%-106.94%-47.99%

Celldex Therapeutics presently has a consensus price target of $61.92, suggesting a potential upside of 95.65%. Silence Therapeutics has a consensus price target of $53.50, suggesting a potential upside of 402.82%. Given Silence Therapeutics' higher probable upside, analysts clearly believe Silence Therapeutics is more favorable than Celldex Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Celldex Therapeutics
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.86
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

Silence Therapeutics has lower revenue, but higher earnings than Celldex Therapeutics. Silence Therapeutics is trading at a lower price-to-earnings ratio than Celldex Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Celldex Therapeutics$1.54M1,613.94-$258.76M-$4.35N/A
Silence Therapeutics$560K1,143.99-$88.61M-$1.28N/A

Celldex Therapeutics has a beta of 0.9, suggesting that its stock price is 10% less volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.45, suggesting that its stock price is 45% more volatile than the broader market.

98.7% of Silence Therapeutics shares are owned by institutional investors. 5.2% of Celldex Therapeutics shares are owned by company insiders. Comparatively, 3.0% of Silence Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Summary

Celldex Therapeutics beats Silence Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Silence Therapeutics compare to Nurix Therapeutics?

Nurix Therapeutics (NASDAQ:NRIX) and Silence Therapeutics (NASDAQ:SLN) are both healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, risk, analyst recommendations, profitability, valuation, dividends, institutional ownership and media sentiment.

Nurix Therapeutics has a net margin of -928.44% compared to Silence Therapeutics' net margin of -8,943.86%. Nurix Therapeutics' return on equity of -76.09% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Nurix Therapeutics-928.44% -76.09% -57.31%
Silence Therapeutics -8,943.86%-106.94%-47.99%

Silence Therapeutics has lower revenue, but higher earnings than Nurix Therapeutics. Silence Therapeutics is trading at a lower price-to-earnings ratio than Nurix Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Nurix Therapeutics$83.98M28.41-$264.46M-$3.45N/A
Silence Therapeutics$560K1,143.99-$88.61M-$1.28N/A

Nurix Therapeutics has a beta of 1.82, suggesting that its share price is 82% more volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.45, suggesting that its share price is 45% more volatile than the broader market.

98.7% of Silence Therapeutics shares are owned by institutional investors. 6.7% of Nurix Therapeutics shares are owned by insiders. Comparatively, 3.0% of Silence Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Nurix Therapeutics currently has a consensus target price of $34.21, suggesting a potential upside of 48.82%. Silence Therapeutics has a consensus target price of $53.50, suggesting a potential upside of 402.82%. Given Silence Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Silence Therapeutics is more favorable than Nurix Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Nurix Therapeutics
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.80
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

In the previous week, Nurix Therapeutics had 7 more articles in the media than Silence Therapeutics. MarketBeat recorded 8 mentions for Nurix Therapeutics and 1 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 0.78 beat Nurix Therapeutics' score of 0.29 indicating that Silence Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Nurix Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Silence Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Silence Therapeutics beats Nurix Therapeutics on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SLN and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SLN vs. The Competition

MetricSilence TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$640.62M$3.87B$7.14B$13.22B
Dividend YieldN/A3.64%2.53%16.78%
P/E Ratio-8.3113.13275.9726.04
Price / Sales1,041.661,434.36672.88109.45
Price / CashN/A122.6077.6051.75
Price / Book8.0616.6310.936.31
Net Income-$88.61M-$22.71M$3.51B$362.16M
7 Day Performance-4.83%-2.99%-2.00%-1.66%
1 Month Performance-28.06%-10.60%-6.15%-4.50%
1 Year Performance112.80%19.44%7.44%2.06%

Silence Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SLN
Silence Therapeutics
2.5465 of 5 stars
$10.64
-0.7%
$53.50
+402.8%
+104.6%$640.62M$615KN/A88
BEAM
Beam Therapeutics
2.6007 of 5 stars
$24.52
+1.2%
$49.00
+99.8%
-4.3%$2.53B$139.74MN/A540
IRON
Disc Medicine
2.5314 of 5 stars
$65.87
+1.5%
$110.18
+67.3%
-2.0%$2.53BN/AN/A165
IMNM
Immunome
2.6458 of 5 stars
$21.89
+1.0%
$35.18
+60.7%
+82.2%$2.49B$6.94MN/A177
CLDX
Celldex Therapeutics
2.028 of 5 stars
$31.64
+0.5%
$61.92
+95.7%
+22.4%$2.48B$1.54MN/A198

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This page (NASDAQ:SLN) was last updated on 10/3/2026 by MarketBeat.com Staff.
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