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Silence Therapeutics (SLN) Competitors

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$9.75 +0.46 (+4.95%)
Closing price 07/14/2026 04:00 PM Eastern
Extended Trading
$9.77 +0.02 (+0.21%)
As of 07/14/2026 06:14 PM Eastern
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SLN vs. ATAI, RAPP, TYRA, TSHA, and MESO

Should you buy Silence Therapeutics stock or one of its competitors? MarketBeat compares Silence Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Silence Therapeutics include Atai Beckley (ATAI), Rapport Therapeutics (RAPP), Tyra Biosciences (TYRA), Taysha Gene Therapies (TSHA), and Mesoblast (MESO). These companies are all part of the "pharmaceutical products" industry.

How does Silence Therapeutics compare to Atai Beckley?

Atai Beckley (NASDAQ:ATAI) and Silence Therapeutics (NASDAQ:SLN) are both small-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their valuation, media sentiment, analyst recommendations, earnings, risk, institutional ownership, profitability and dividends.

Silence Therapeutics has a net margin of -8,943.86% compared to Atai Beckley's net margin of -19,019.44%. Atai Beckley's return on equity of -89.79% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Atai Beckley-19,019.44% -89.79% -63.58%
Silence Therapeutics -8,943.86%-105.34%-52.79%

28.4% of Atai Beckley shares are held by institutional investors. Comparatively, 98.7% of Silence Therapeutics shares are held by institutional investors. 19.8% of Atai Beckley shares are held by insiders. Comparatively, 3.0% of Silence Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Silence Therapeutics has lower revenue, but higher earnings than Atai Beckley. Silence Therapeutics is trading at a lower price-to-earnings ratio than Atai Beckley, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Atai Beckley$4.09M510.40-$660.05M-$2.23N/A
Silence Therapeutics$560K822.48-$88.61M-$1.59N/A

In the previous week, Atai Beckley had 2 more articles in the media than Silence Therapeutics. MarketBeat recorded 5 mentions for Atai Beckley and 3 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 1.65 beat Atai Beckley's score of 0.62 indicating that Silence Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Atai Beckley
1 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Atai Beckley presently has a consensus target price of $15.50, indicating a potential upside of 173.37%. Silence Therapeutics has a consensus target price of $55.00, indicating a potential upside of 464.10%. Given Silence Therapeutics' higher possible upside, analysts plainly believe Silence Therapeutics is more favorable than Atai Beckley.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Atai Beckley
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
2.92
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

Atai Beckley has a beta of 1.56, indicating that its stock price is 56% more volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.38, indicating that its stock price is 38% more volatile than the broader market.

Summary

Atai Beckley beats Silence Therapeutics on 9 of the 17 factors compared between the two stocks.

How does Silence Therapeutics compare to Rapport Therapeutics?

Rapport Therapeutics (NASDAQ:RAPP) and Silence Therapeutics (NASDAQ:SLN) are both small-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their analyst recommendations, earnings, valuation, dividends, media sentiment, risk, profitability and institutional ownership.

Silence Therapeutics has higher revenue and earnings than Rapport Therapeutics. Rapport Therapeutics is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rapport TherapeuticsN/AN/A-$111.48M-$2.60N/A
Silence Therapeutics$560K822.48-$88.61M-$1.59N/A

In the previous week, Rapport Therapeutics had 2 more articles in the media than Silence Therapeutics. MarketBeat recorded 5 mentions for Rapport Therapeutics and 3 mentions for Silence Therapeutics. Rapport Therapeutics' average media sentiment score of 1.69 beat Silence Therapeutics' score of 1.65 indicating that Rapport Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rapport Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Rapport Therapeutics has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Rapport Therapeutics' return on equity of -24.78% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Rapport TherapeuticsN/A -24.78% -23.44%
Silence Therapeutics -8,943.86%-105.34%-52.79%

Rapport Therapeutics has a beta of 0.94, indicating that its stock price is 6% less volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.38, indicating that its stock price is 38% more volatile than the broader market.

Rapport Therapeutics currently has a consensus price target of $57.86, indicating a potential upside of 39.55%. Silence Therapeutics has a consensus price target of $55.00, indicating a potential upside of 464.10%. Given Silence Therapeutics' higher probable upside, analysts clearly believe Silence Therapeutics is more favorable than Rapport Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rapport Therapeutics
1 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.91
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

98.7% of Silence Therapeutics shares are owned by institutional investors. 12.5% of Rapport Therapeutics shares are owned by company insiders. Comparatively, 3.0% of Silence Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Summary

Rapport Therapeutics beats Silence Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Silence Therapeutics compare to Tyra Biosciences?

Silence Therapeutics (NASDAQ:SLN) and Tyra Biosciences (NASDAQ:TYRA) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their valuation, profitability, institutional ownership, media sentiment, earnings, dividends, risk and analyst recommendations.

Silence Therapeutics has a beta of 1.38, indicating that its stock price is 38% more volatile than the broader market. Comparatively, Tyra Biosciences has a beta of 0.76, indicating that its stock price is 24% less volatile than the broader market.

Tyra Biosciences has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Tyra Biosciences' return on equity of -42.66% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Silence Therapeutics-8,943.86% -105.34% -52.79%
Tyra Biosciences N/A -42.66%-39.79%

Silence Therapeutics currently has a consensus price target of $55.00, suggesting a potential upside of 464.10%. Tyra Biosciences has a consensus price target of $47.00, suggesting a potential upside of 42.94%. Given Silence Therapeutics' higher probable upside, analysts plainly believe Silence Therapeutics is more favorable than Tyra Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Tyra Biosciences
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87

Silence Therapeutics has higher revenue and earnings than Tyra Biosciences. Tyra Biosciences is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Silence Therapeutics$560K822.48-$88.61M-$1.59N/A
Tyra BiosciencesN/AN/A-$119.95M-$2.18N/A

In the previous week, Silence Therapeutics had 1 more articles in the media than Tyra Biosciences. MarketBeat recorded 3 mentions for Silence Therapeutics and 2 mentions for Tyra Biosciences. Silence Therapeutics' average media sentiment score of 1.65 beat Tyra Biosciences' score of 1.61 indicating that Silence Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Tyra Biosciences
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

98.7% of Silence Therapeutics shares are held by institutional investors. Comparatively, 84.1% of Tyra Biosciences shares are held by institutional investors. 3.0% of Silence Therapeutics shares are held by insiders. Comparatively, 12.5% of Tyra Biosciences shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Summary

Silence Therapeutics beats Tyra Biosciences on 9 of the 15 factors compared between the two stocks.

How does Silence Therapeutics compare to Taysha Gene Therapies?

Taysha Gene Therapies (NASDAQ:TSHA) and Silence Therapeutics (NASDAQ:SLN) are both small-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their earnings, institutional ownership, valuation, risk, dividends, profitability, media sentiment and analyst recommendations.

Taysha Gene Therapies has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Taysha Gene Therapies' return on equity of -56.07% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Taysha Gene TherapiesN/A -56.07% -40.16%
Silence Therapeutics -8,943.86%-105.34%-52.79%

Taysha Gene Therapies has a beta of 1.17, indicating that its share price is 17% more volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.38, indicating that its share price is 38% more volatile than the broader market.

Silence Therapeutics has lower revenue, but higher earnings than Taysha Gene Therapies. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Taysha Gene Therapies$9.77M167.65-$109M-$0.38N/A
Silence Therapeutics$560K822.48-$88.61M-$1.59N/A

77.7% of Taysha Gene Therapies shares are owned by institutional investors. Comparatively, 98.7% of Silence Therapeutics shares are owned by institutional investors. 3.5% of Taysha Gene Therapies shares are owned by company insiders. Comparatively, 3.0% of Silence Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Taysha Gene Therapies presently has a consensus price target of $12.62, suggesting a potential upside of 121.32%. Silence Therapeutics has a consensus price target of $55.00, suggesting a potential upside of 464.10%. Given Silence Therapeutics' higher possible upside, analysts plainly believe Silence Therapeutics is more favorable than Taysha Gene Therapies.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
3.00
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

In the previous week, Taysha Gene Therapies had 3 more articles in the media than Silence Therapeutics. MarketBeat recorded 6 mentions for Taysha Gene Therapies and 3 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 1.65 beat Taysha Gene Therapies' score of 0.83 indicating that Silence Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Taysha Gene Therapies
2 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Summary

Taysha Gene Therapies beats Silence Therapeutics on 10 of the 17 factors compared between the two stocks.

How does Silence Therapeutics compare to Mesoblast?

Mesoblast (NASDAQ:MESO) and Silence Therapeutics (NASDAQ:SLN) are both medical companies, but which is the superior stock? We will compare the two companies based on the strength of their media sentiment, analyst recommendations, profitability, earnings, valuation, dividends, institutional ownership and risk.

Mesoblast has a beta of 2.08, suggesting that its share price is 108% more volatile than the broader market. Comparatively, Silence Therapeutics has a beta of 1.38, suggesting that its share price is 38% more volatile than the broader market.

Silence Therapeutics has a consensus target price of $55.00, indicating a potential upside of 464.10%. Given Silence Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Silence Therapeutics is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mesoblast
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33
Silence Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

Mesoblast has a net margin of 0.00% compared to Silence Therapeutics' net margin of -8,943.86%. Mesoblast's return on equity of 0.00% beat Silence Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
MesoblastN/A N/A N/A
Silence Therapeutics -8,943.86%-105.34%-52.79%

Silence Therapeutics has lower revenue, but higher earnings than Mesoblast. Mesoblast is trading at a lower price-to-earnings ratio than Silence Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mesoblast$17.20M126.00-$102.14M-$0.28N/A
Silence Therapeutics$560K822.48-$88.61M-$1.59N/A

1.4% of Mesoblast shares are held by institutional investors. Comparatively, 98.7% of Silence Therapeutics shares are held by institutional investors. 18.8% of Mesoblast shares are held by insiders. Comparatively, 3.0% of Silence Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

In the previous week, Mesoblast had 12 more articles in the media than Silence Therapeutics. MarketBeat recorded 15 mentions for Mesoblast and 3 mentions for Silence Therapeutics. Silence Therapeutics' average media sentiment score of 1.65 beat Mesoblast's score of 0.13 indicating that Silence Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mesoblast
3 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
4 Negative mention(s)
2 Very Negative mention(s)
Neutral
Silence Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Summary

Mesoblast and Silence Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SLN and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SLN vs. The Competition

MetricSilence TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$438.81M$3.02B$6.86B$12.44B
Dividend YieldN/A2.08%2.68%8.42%
P/E Ratio-6.1318.7727.0124.38
Price / Sales822.48344.35519.4391.92
Price / CashN/A56.8348.5959.36
Price / Book7.394.2010.806.33
Net Income-$88.61M$65.13M$3.59B$331.02M
7 Day Performance-2.01%-2.63%-1.47%-0.33%
1 Month Performance39.29%2.14%2.78%-1.29%
1 Year Performance50.23%23.26%28.50%21.30%

Silence Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SLN
Silence Therapeutics
3.8107 of 5 stars
$9.75
+5.0%
$55.00
+464.1%
+55.3%$438.81M$560KN/A100
ATAI
Atai Beckley
3.5975 of 5 stars
$5.19
+4.6%
$15.50
+198.7%
+108.5%$1.91B$4.09MN/A80
RAPP
Rapport Therapeutics
3.0914 of 5 stars
$39.72
+3.0%
$57.86
+45.7%
+183.4%$1.90BN/AN/AN/A
TYRA
Tyra Biosciences
2.6485 of 5 stars
$31.94
+3.5%
$47.00
+47.2%
+201.4%$1.90BN/AN/A20
TSHA
Taysha Gene Therapies
3.507 of 5 stars
$6.50
+1.9%
$12.62
+94.1%
+115.9%$1.87B$9.77MN/A180

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This page (NASDAQ:SLN) was last updated on 7/15/2026 by MarketBeat.com Staff.
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