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Vertex Pharmaceuticals (VRTX) Stock Forecast & Price Target

Vertex Pharmaceuticals logo
$388.55 -7.93 (-2.00%)
Closing price 09/10/2025 04:00 PM Eastern
Extended Trading
$390.97 +2.42 (+0.62%)
As of 09:22 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Vertex Pharmaceuticals - Analysts' Recommendations and Stock Price Forecast (2025)

Consensus Rating

Sell
0
Hold
13
Buy
14

Based on 27 Wall Street analysts who have issued ratings for Vertex Pharmaceuticals in the last 12 months, the stock has a consensus rating of "Moderate Buy." Out of the 27 analysts, 13 have given a hold rating, 13 have given a buy rating, and 1 has given a strong buy rating for VRTX.

Consensus Price Target

$497.10
27.94% Upside
According to the 27 analysts' twelve-month price targets for Vertex Pharmaceuticals, the average price target is $497.10. The highest price target for VRTX is $575.00, while the lowest price target for VRTX is $405.00. The average price target represents a forecasted upside of 27.94% from the current price of $388.55.
MarketBeat calculates consensus analyst ratings for stocks using the most recent rating from each Wall Street analyst that has rated a stock within the last twelve months. Each analyst's rating is normalized to a standardized rating score of 1 (sell), 2 (hold), 3 (buy) or 4 (strong buy). Analyst consensus ratings scores are calculated using the mean average of the number of normalized sell, hold, buy and strong buy ratings from Wall Street analysts. Each stock's consensus analyst rating is derived from its calculated consensus ratings score (0 to .5 = Strong Sell, .5 to 1 = Sell, 1 to 1.5 = Reduce, 1.5 to 2.5 = Hold, 2.5 to 3.0 = Moderate Buy, 3.0 to 3.5 = Buy, >3.5 = Strong Buy). MarketBeat's consensus price targets are a mean average of the most recent available price targets set by each analyst that has set a price target for the stock in the last twelve months. MarketBeat's consensus ratings and consensus price targets may differ from those calculated by other firms due to differences in methodology and available data.
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VRTX Analyst Ratings Over Time

TypeCurrent Forecast
9/11/24 to 9/11/25
1 Month Ago
8/12/24 to 8/12/25
3 Months Ago
6/13/24 to 6/13/25
1 Year Ago
9/12/23 to 9/11/24
Strong Buy
1 Strong Buy rating(s)
1 Strong Buy rating(s)
1 Strong Buy rating(s)
0 Strong Buy rating(s)
Buy
13 Buy rating(s)
13 Buy rating(s)
15 Buy rating(s)
16 Buy rating(s)
Hold
13 Hold rating(s)
13 Hold rating(s)
14 Hold rating(s)
7 Hold rating(s)
Sell
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
3 Sell rating(s)
Consensus Price Target$497.10$497.10$515.04$485.91
Forecasted Upside27.94% Upside28.19% Upside13.08% Upside2.35% Upside
Consensus RatingModerate BuyModerate BuyModerate BuyModerate Buy

VRTX Analyst Recommendations By Month

The chart below shows how a company's ratings by analysts have changed over time. Each bar represents the previous year of ratings for that month. Within each bar, the sell ratings are shown in red, the hold ratings are shown in yellow, the buy ratings are shown in green, and the strong buy ratings are shown in dark green.
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VRTX Price Targets by Month

The chart below shows how a company's share price and consensus price target have changed over time. The dark blue line represents the company's actual price. The lighter blue line represents the stock's consensus price target. The even lighter blue range in the background of the two lines represents the low price target and the high price target for each stock.
Skip Chart and View Analyst Price Target HistorySkip Chart & View Price History Table

Vertex Pharmaceuticals Stock vs. The Competition

TypeVertex PharmaceuticalsMedical CompaniesS&P 500
Consensus Rating Score
2.56
2.78
2.53
Consensus RatingModerate BuyModerate BuyModerate Buy
Predicted Upside27.94% Upside17,070.71% Upside11.30% Upside
News Sentiment Rating
Positive News

See Recent VRTX News
Positive News
Positive News
DateBrokerageAnalystActionRatingPrice TargetReport Date
Upside/Downside
Details
9/2/2025Raymond James Financial
4 of 5 stars
Danielle Brill
Not Rated
Initiated CoverageMarket Perform
8/6/2025Canaccord Genuity Group
2 of 5 stars
Whitney Ijem
Not Rated
Lower TargetHold$424.00 ➝ $411.00+6.45%
8/6/2025Guggenheim
2 of 5 stars
Lower TargetBuy$558.00 ➝ $546.00+40.91%
8/6/2025Wells Fargo & Company
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UpgradeEqual WeightOverweight$460.00+22.67%
8/5/2025Scotiabank
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Lower TargetSector Perform$442.00 ➝ $438.00+11.47%
8/5/2025Truist Financial
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Set TargetBuy$520.00 ➝ $490.00+24.70%
8/5/2025Royal Bank Of Canada
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Lower TargetSector Perform$430.00 ➝ $405.00+3.86%
8/5/2025UBS Group
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Set TargetBuy$582.00 ➝ $553.00+37.88%
8/5/2025BMO Capital Markets
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Set TargetOutperform$557.00 ➝ $530.00+12.22%
8/5/2025Cantor Fitzgerald
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Lower TargetOverweight$535.00 ➝ $485.00+2.70%
8/5/2025Stifel Nicolaus
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Lower TargetHold$494.00 ➝ $455.00-3.66%
8/5/2025HC Wainwright
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Lower TargetBuy$550.00 ➝ $478.00+1.21%
8/5/2025Morgan Stanley
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Set TargetEqual Weight$460.00 ➝ $439.00-7.04%
7/14/2025JPMorgan Chase & Co.
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Boost TargetOverweight$515.00 ➝ $517.00+9.43%
5/23/2025Erste Group Bank
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DowngradeStrong-BuyHold
5/7/2025Wolfe Research
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DowngradeOutperformPeer Perform
5/6/2025The Goldman Sachs Group
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 Reiterated RatingBuy
5/6/2025Leerink Partnrs
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DowngradeStrong-BuyHold
5/6/2025William Blair
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 Reiterated RatingOutperform
5/6/2025Leerink Partners
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Reiterated RatingOutperformMarket Perform$550.00 ➝ $503.00+0.56%
5/6/2025Needham & Company LLC
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Reiterated RatingHold
3/31/2025Bank of America
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Boost TargetBuy$555.00 ➝ $567.00+15.08%
2/11/2025Barclays
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Boost TargetEqual Weight$435.00 ➝ $467.00+1.35%
1/27/2025Piper Sandler
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Lower TargetOverweight$535.00 ➝ $533.00+20.72%
12/19/2024Oppenheimer
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 DowngradeOutperformMarket Perform
12/9/2024Jefferies Financial Group
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 UpgradeHoldBuy$500.00 ➝ $550.00+19.02%
11/14/2024Citigroup
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 Initiated CoverageBuy$575.00+16.25%
7/23/2024TD Cowen
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 Boost TargetBuy$450.00 ➝ $500.00+1.60%
6/27/2024Redburn Atlantic
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Initiated CoverageBuy$545.00+14.98%
6/17/2024Argus
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 Boost TargetBuy$465.00 ➝ $550.00+15.48%
4/11/2024Evercore ISI
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 UpgradeIn-LineOutperform$438.00+10.17%
2/2/2024Sanford C. Bernstein
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 DowngradeOutperformMarket Perform
1/31/2024Robert W. Baird
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 DowngradeNeutralUnderperform$325.00-25.27%
1/31/2024Maxim Group
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 DowngradeBuyHold

Analyst ratings data on MarketBeat is provided by Benzinga and other data providers. This page was last refreshed on Thursday at 09:22 AM ET.


Should I Buy Vertex Pharmaceuticals Stock? VRTX Pros and Cons Explained

These pros and cons were generated based on recent news and financial data from MarketBeat in order to provide readers with the fastest and most accurate insights. They were last updated on Sunday, September 7, 2025. Please send any questions or comments about these Vertex Pharmaceuticals pros and cons to contact@marketbeat.com.

Vertex Pharmaceuticals
Bull Case

green Wall Street bull icon

Here are some ways that investors could benefit from investing in Vertex Pharmaceuticals Incorporated:

  • The current stock price is around $396, which may present a buying opportunity for investors looking for growth in the biotechnology sector.
  • Vertex Pharmaceuticals has demonstrated strong financial performance, reporting a significant increase in quarterly revenue compared to the previous year, indicating robust business growth.
  • The company has a solid market capitalization of approximately $101.56 billion, reflecting its stability and potential for future growth in the biotechnology market.
  • Vertex Pharmaceuticals has received positive ratings from analysts, with a consensus rating of "Moderate Buy," suggesting confidence in the company's future performance.
  • Recent insider buying activity, with a director purchasing shares, can signal confidence in the company's prospects and may encourage other investors to consider buying in.

Vertex Pharmaceuticals
Bear Case

red Wall Street bear icon

Investors should be bearish about investing in Vertex Pharmaceuticals Incorporated for these reasons:

  • Despite recent growth, the stock has experienced fluctuations, with a 1-year high of $519.88 and a low of $362.50, indicating potential volatility that could concern risk-averse investors.
  • Analysts have adjusted price targets downward, which may reflect concerns about future performance and could lead to decreased investor confidence.
  • The company has a relatively high price-to-earnings (P/E) ratio of 28.31, which may suggest that the stock is overvalued compared to its earnings, potentially deterring value-focused investors.
  • Institutional investors and hedge funds own a significant majority (90.96%) of the company's stock, which could lead to less control for individual investors and increased volatility based on institutional trading decisions.
  • With only 0.20% of the stock owned by insiders, there may be less alignment between management and shareholder interests, which could be a red flag for some investors.

VRTX Forecast - Frequently Asked Questions

According to the research reports of 27 Wall Street equities research analysts, the average twelve-month stock price forecast for Vertex Pharmaceuticals is $497.10, with a high forecast of $575.00 and a low forecast of $405.00.

27 Wall Street research analysts have issued "buy," "hold," and "sell" ratings for Vertex Pharmaceuticals in the last year. There are currently 13 hold ratings, 13 buy ratings and 1 strong buy rating for the stock. The consensus among Wall Street research analysts is that investors should "moderate buy" VRTX shares.

According to analysts, Vertex Pharmaceuticals's stock has a predicted upside of 27.94% based on their 12-month stock forecasts.

Over the previous 90 days, Vertex Pharmaceuticals's stock had 1 upgrade by analysts.

Analysts like Vertex Pharmaceuticals less than other "medical" companies. The consensus rating score for Vertex Pharmaceuticals is 2.56 while the average consensus rating score for "medical" companies is 2.78. Learn more on how VRTX compares to other companies.


This page (NASDAQ:VRTX) was last updated on 9/11/2025 by MarketBeat.com Staff
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