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Vertex Pharmaceuticals (VRTX) Stock Forecast & Price Target

Vertex Pharmaceuticals logo
$403.30 -5.55 (-1.36%)
Closing price 10/3/2025 04:00 PM Eastern
Extended Trading
$403.82 +0.51 (+0.13%)
As of 10/3/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Vertex Pharmaceuticals - Analysts' Recommendations and Stock Price Forecast (2025)

Consensus Rating

Sell
0
Hold
12
Buy
17

Based on 29 Wall Street analysts who have issued ratings for Vertex Pharmaceuticals in the last 12 months, the stock has a consensus rating of "Moderate Buy." Out of the 29 analysts, 12 have given a hold rating, 16 have given a buy rating, and 1 has given a strong buy rating for VRTX.

Consensus Price Target

$493.81
22.44% Upside
According to the 29 analysts' twelve-month price targets for Vertex Pharmaceuticals, the average price target is $493.81. The highest price target for VRTX is $575.00, while the lowest price target for VRTX is $405.00. The average price target represents a forecasted upside of 22.44% from the current price of $403.30.
MarketBeat calculates consensus analyst ratings for stocks using the most recent rating from each Wall Street analyst that has rated a stock within the last twelve months. Each analyst's rating is normalized to a standardized rating score of 1 (sell), 2 (hold), 3 (buy) or 4 (strong buy). Analyst consensus ratings scores are calculated using the mean average of the number of normalized sell, hold, buy and strong buy ratings from Wall Street analysts. Each stock's consensus analyst rating is derived from its calculated consensus ratings score (0 to .5 = Strong Sell, .5 to 1 = Sell, 1 to 1.5 = Reduce, 1.5 to 2.5 = Hold, 2.5 to 3.0 = Moderate Buy, 3.0 to 3.5 = Buy, >3.5 = Strong Buy). MarketBeat's consensus price targets are a mean average of the most recent available price targets set by each analyst that has set a price target for the stock in the last twelve months. MarketBeat's consensus ratings and consensus price targets may differ from those calculated by other firms due to differences in methodology and available data.
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VRTX Analyst Ratings Over Time

TypeCurrent Forecast
10/4/24 to 10/4/25
1 Month Ago
9/4/24 to 9/4/25
3 Months Ago
7/6/24 to 7/6/25
1 Year Ago
10/5/23 to 10/4/24
Strong Buy
1 Strong Buy rating(s)
1 Strong Buy rating(s)
1 Strong Buy rating(s)
0 Strong Buy rating(s)
Buy
16 Buy rating(s)
13 Buy rating(s)
13 Buy rating(s)
16 Buy rating(s)
Hold
12 Hold rating(s)
13 Hold rating(s)
14 Hold rating(s)
7 Hold rating(s)
Sell
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
3 Sell rating(s)
Consensus Price Target$493.81$497.10$511.62$486.95
Forecasted Upside22.44% Upside25.24% Upside12.53% Upside6.95% Upside
Consensus RatingModerate BuyModerate BuyModerate BuyModerate Buy

VRTX Analyst Recommendations By Month

The chart below shows how a company's ratings by analysts have changed over time. Each bar represents the previous year of ratings for that month. Within each bar, the sell ratings are shown in red, the hold ratings are shown in yellow, the buy ratings are shown in green, and the strong buy ratings are shown in dark green.
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VRTX Price Targets by Month

The chart below shows how a company's share price and consensus price target have changed over time. The dark blue line represents the company's actual price. The lighter blue line represents the stock's consensus price target. The even lighter blue range in the background of the two lines represents the low price target and the high price target for each stock.
Skip Chart and View Analyst Price Target HistorySkip Chart & View Price History Table

Vertex Pharmaceuticals Stock vs. The Competition

TypeVertex PharmaceuticalsMedical CompaniesS&P 500
Consensus Rating Score
2.62
2.69
2.52
Consensus RatingModerate BuyModerate BuyModerate Buy
Predicted Upside22.44% Upside1,376.64% Upside10.49% Upside
News Sentiment Rating
Positive News

See Recent VRTX News
Positive News
Positive News
DateBrokerageAnalystActionRatingPrice TargetReport Date
Upside/Downside
Details
10/2/2025Citigroup
3 of 5 stars
Geoff Meacham
Geoff Meacham
Not Rated
Boost TargetBuy$550.00 ➝ $575.00+40.80%
9/27/2025Weiss Ratings
0 of 5 stars
 Reiterated RatingHold (C+)
9/25/2025Leerink Partnrs
1 of 5 stars
 UpgradeHoldStrong-Buy
9/25/2025Leerink Partners
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UpgradeMarket PerformOutperform$458.00 ➝ $456.00+21.08%
9/11/2025Evercore ISI
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Lower TargetOutperform$510.00 ➝ $475.00+21.55%
9/2/2025Raymond James Financial
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Initiated CoverageMarket Perform
8/6/2025Canaccord Genuity Group
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Lower TargetHold$424.00 ➝ $411.00+6.45%
8/6/2025Guggenheim
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Lower TargetBuy$558.00 ➝ $546.00+40.91%
8/6/2025Wells Fargo & Company
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UpgradeEqual WeightOverweight$460.00+22.67%
8/5/2025Scotiabank
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Lower TargetSector Perform$442.00 ➝ $438.00+11.47%
8/5/2025Truist Financial
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Set TargetBuy$520.00 ➝ $490.00+24.70%
8/5/2025Royal Bank Of Canada
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Lower TargetSector Perform$430.00 ➝ $405.00+3.86%
8/5/2025UBS Group
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Set TargetBuy$582.00 ➝ $553.00+37.88%
8/5/2025BMO Capital Markets
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Set TargetOutperform$557.00 ➝ $530.00+12.22%
8/5/2025Cantor Fitzgerald
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Lower TargetOverweight$535.00 ➝ $485.00+2.70%
8/5/2025Stifel Nicolaus
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Lower TargetHold$494.00 ➝ $455.00-3.66%
8/5/2025HC Wainwright
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Lower TargetBuy$550.00 ➝ $478.00+1.21%
8/5/2025Morgan Stanley
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Set TargetEqual Weight$460.00 ➝ $439.00-7.04%
7/14/2025JPMorgan Chase & Co.
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Boost TargetOverweight$515.00 ➝ $517.00+9.43%
5/23/2025Erste Group Bank
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DowngradeStrong-BuyHold
5/7/2025Wolfe Research
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DowngradeOutperformPeer Perform
5/6/2025The Goldman Sachs Group
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 Reiterated RatingBuy
5/6/2025William Blair
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 Reiterated RatingOutperform
5/6/2025Needham & Company LLC
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Reiterated RatingHold
3/31/2025Bank of America
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Boost TargetBuy$555.00 ➝ $567.00+15.08%
2/11/2025Barclays
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Boost TargetEqual Weight$435.00 ➝ $467.00+1.35%
1/27/2025Piper Sandler
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Lower TargetOverweight$535.00 ➝ $533.00+20.72%
12/19/2024Oppenheimer
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 DowngradeOutperformMarket Perform
12/9/2024Jefferies Financial Group
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 UpgradeHoldBuy$500.00 ➝ $550.00+19.02%
7/23/2024TD Cowen
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 Boost TargetBuy$450.00 ➝ $500.00+1.60%
6/27/2024Redburn Atlantic
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Initiated CoverageBuy$545.00+14.98%
6/17/2024Argus
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 Boost TargetBuy$465.00 ➝ $550.00+15.48%
2/2/2024Sanford C. Bernstein
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 DowngradeOutperformMarket Perform
1/31/2024Robert W. Baird
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 DowngradeNeutralUnderperform$325.00-25.27%
1/31/2024Maxim Group
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 DowngradeBuyHold

Analyst ratings data on MarketBeat is provided by Benzinga and other data providers. This page was last refreshed on Saturday at 01:59 AM ET.


Should I Buy Vertex Pharmaceuticals Stock? VRTX Pros and Cons Explained

These pros and cons were generated based on recent news and financial data from MarketBeat in order to provide readers with the fastest and most accurate insights. They were last updated on Friday, October 3, 2025. Please send any questions or comments about these Vertex Pharmaceuticals pros and cons to contact@marketbeat.com.

Vertex Pharmaceuticals
Bull Case

green Wall Street bull icon

Here are some ways that investors could benefit from investing in Vertex Pharmaceuticals Incorporated:

  • The company recently reported strong earnings, with an EPS of $4.52, exceeding expectations, indicating robust financial health and operational efficiency.
  • Vertex Pharmaceuticals Incorporated has shown significant revenue growth, with a year-over-year increase of 11.3%, suggesting a strong demand for its products.
  • Analysts have a consensus rating of "Moderate Buy" for the stock, with an average price target of approximately $493.81, indicating potential for price appreciation.
  • The current stock price is around $408.25, which may present a buying opportunity for investors looking to enter at a favorable level.
  • Recent analyst upgrades, including a target price increase from Citigroup to $575.00, reflect positive sentiment and confidence in the company's future performance.

Vertex Pharmaceuticals
Bear Case

red Wall Street bear icon

Investors should be bearish about investing in Vertex Pharmaceuticals Incorporated for these reasons:

  • Despite recent growth, the stock has experienced volatility, with a 52-week range showing a low of $362.50 and a high of $519.88, indicating potential risks associated with price fluctuations.
  • Some analysts have downgraded their price targets, suggesting a cautious outlook on the stock's short-term performance.
  • The company faces competition in the biotechnology sector, which could impact its market share and profitability in the future.
  • Insider ownership is relatively low at 0.20%, which may raise concerns about alignment between management and shareholder interests.
  • The pharmaceutical industry is subject to regulatory scrutiny, and any adverse regulatory changes could negatively affect Vertex Pharmaceuticals Incorporated's operations and stock performance.

VRTX Forecast - Frequently Asked Questions

According to the research reports of 29 Wall Street equities research analysts, the average twelve-month stock price forecast for Vertex Pharmaceuticals is $493.81, with a high forecast of $575.00 and a low forecast of $405.00.

29 Wall Street research analysts have issued "buy," "hold," and "sell" ratings for Vertex Pharmaceuticals in the last twelve months. There are currently 12 hold ratings, 16 buy ratings and 1 strong buy rating for the stock. The consensus among Wall Street research analysts is that investors should "moderate buy" VRTX shares.

According to analysts, Vertex Pharmaceuticals's stock has a predicted upside of 22.44% based on their 12-month stock forecasts.

Over the previous 90 days, Vertex Pharmaceuticals's stock had 3 upgrades by analysts.

Analysts like Vertex Pharmaceuticals more than other "medical" companies. The consensus rating for Vertex Pharmaceuticals is Moderate Buy while the average consensus rating for "medical" companies is Hold. Learn more on how VRTX compares to other companies.


This page (NASDAQ:VRTX) was last updated on 10/4/2025 by MarketBeat.com Staff
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