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CareDx (CDNA) Competitors

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$47.07 +0.38 (+0.81%)
As of 04:00 PM Eastern

CDNA vs. PTGX, SYRE, IONS, PRAX, and KYMR

Should you buy CareDx stock or one of its competitors? CareDx's main competitors and comparable companies include Protagonist Therapeutics (PTGX), Spyre Therapeutics (SYRE), Ionis Pharmaceuticals (IONS), Praxis Precision Medicines (PRAX), and Kymera Therapeutics (KYMR). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does CareDx compare to Protagonist Therapeutics?

Protagonist Therapeutics (NASDAQ:PTGX) and CareDx (NASDAQ:CDNA) are both mid-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their risk, valuation, analyst recommendations, earnings, media sentiment, profitability, institutional ownership and dividends.

Protagonist Therapeutics has a net margin of 29.40% compared to CareDx's net margin of 24.23%. Protagonist Therapeutics' return on equity of 12.03% beat CareDx's return on equity.

Company Net Margins Return on Equity Return on Assets
Protagonist Therapeutics29.40% 12.03% 11.23%
CareDx 24.23%2.87%2.17%

CareDx has higher revenue and earnings than Protagonist Therapeutics. CareDx is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protagonist Therapeutics$46.02M209.62-$130.15M$1.03145.63
CareDx$379.80M6.41-$21.35M$2.0722.74

In the previous week, Protagonist Therapeutics had 9 more articles in the media than CareDx. MarketBeat recorded 25 mentions for Protagonist Therapeutics and 16 mentions for CareDx. CareDx's average media sentiment score of 0.70 beat Protagonist Therapeutics' score of 0.53 indicating that CareDx is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protagonist Therapeutics
4 Very Positive mention(s)
3 Positive mention(s)
7 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive
CareDx
7 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

98.6% of Protagonist Therapeutics shares are held by institutional investors. 5.2% of Protagonist Therapeutics shares are held by company insiders. Comparatively, 2.4% of CareDx shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Protagonist Therapeutics has a beta of 1.78, indicating that its stock price is 78% more volatile than the broader market. Comparatively, CareDx has a beta of 2.38, indicating that its stock price is 138% more volatile than the broader market.

Protagonist Therapeutics currently has a consensus price target of $137.86, indicating a potential downside of 8.10%. CareDx has a consensus price target of $47.75, indicating a potential upside of 1.44%. Given CareDx's higher possible upside, analysts plainly believe CareDx is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protagonist Therapeutics
1 Sell rating(s)
0 Hold rating(s)
15 Buy rating(s)
2 Strong Buy rating(s)
3.00
CareDx
1 Sell rating(s)
3 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.43

Summary

Protagonist Therapeutics beats CareDx on 10 of the 17 factors compared between the two stocks.

How does CareDx compare to Spyre Therapeutics?

Spyre Therapeutics (NASDAQ:SYRE) and CareDx (NASDAQ:CDNA) are both mid-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their media sentiment, earnings, dividends, profitability, institutional ownership, risk, analyst recommendations and valuation.

CareDx has higher revenue and earnings than Spyre Therapeutics. Spyre Therapeutics is trading at a lower price-to-earnings ratio than CareDx, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Spyre Therapeutics$890K10,407.55-$155.20M-$1.95N/A
CareDx$379.80M6.41-$21.35M$2.0722.74

In the previous week, Spyre Therapeutics had 8 more articles in the media than CareDx. MarketBeat recorded 24 mentions for Spyre Therapeutics and 16 mentions for CareDx. CareDx's average media sentiment score of 0.70 beat Spyre Therapeutics' score of 0.62 indicating that CareDx is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Spyre Therapeutics
8 Very Positive mention(s)
5 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
CareDx
7 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Spyre Therapeutics has a beta of 3.03, suggesting that its stock price is 203% more volatile than the broader market. Comparatively, CareDx has a beta of 2.38, suggesting that its stock price is 138% more volatile than the broader market.

Spyre Therapeutics presently has a consensus target price of $110.15, suggesting a potential upside of 4.58%. CareDx has a consensus target price of $47.75, suggesting a potential upside of 1.44%. Given Spyre Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Spyre Therapeutics is more favorable than CareDx.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Spyre Therapeutics
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87
CareDx
1 Sell rating(s)
3 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.43

80.4% of Spyre Therapeutics shares are owned by institutional investors. 15.7% of Spyre Therapeutics shares are owned by insiders. Comparatively, 2.4% of CareDx shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

CareDx has a net margin of 24.23% compared to Spyre Therapeutics' net margin of 0.00%. CareDx's return on equity of 2.87% beat Spyre Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Spyre TherapeuticsN/A -30.74% -22.23%
CareDx 24.23%2.87%2.17%

Summary

Spyre Therapeutics beats CareDx on 8 of the 15 factors compared between the two stocks.

How does CareDx compare to Ionis Pharmaceuticals?

Ionis Pharmaceuticals (NASDAQ:IONS) and CareDx (NASDAQ:CDNA) are both mid-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their media sentiment, institutional ownership, risk, dividends, analyst recommendations, profitability, earnings and valuation.

CareDx has a net margin of 24.23% compared to Ionis Pharmaceuticals' net margin of -64.76%. CareDx's return on equity of 2.87% beat Ionis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ionis Pharmaceuticals-64.76% -111.08% -17.41%
CareDx 24.23%2.87%2.17%

Ionis Pharmaceuticals has a beta of 0.41, meaning that its share price is 59% less volatile than the broader market. Comparatively, CareDx has a beta of 2.38, meaning that its share price is 138% more volatile than the broader market.

In the previous week, Ionis Pharmaceuticals had 2 more articles in the media than CareDx. MarketBeat recorded 18 mentions for Ionis Pharmaceuticals and 16 mentions for CareDx. CareDx's average media sentiment score of 0.70 beat Ionis Pharmaceuticals' score of 0.19 indicating that CareDx is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ionis Pharmaceuticals
2 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Neutral
CareDx
7 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Ionis Pharmaceuticals presently has a consensus target price of $94.65, indicating a potential upside of 66.23%. CareDx has a consensus target price of $47.75, indicating a potential upside of 1.44%. Given Ionis Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Ionis Pharmaceuticals is more favorable than CareDx.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ionis Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
18 Buy rating(s)
0 Strong Buy rating(s)
2.77
CareDx
1 Sell rating(s)
3 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.43

CareDx has lower revenue, but higher earnings than Ionis Pharmaceuticals. Ionis Pharmaceuticals is trading at a lower price-to-earnings ratio than CareDx, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ionis Pharmaceuticals$944M10.02-$381.39M-$3.46N/A
CareDx$379.80M6.41-$21.35M$2.0722.74

93.9% of Ionis Pharmaceuticals shares are owned by institutional investors. 1.8% of Ionis Pharmaceuticals shares are owned by company insiders. Comparatively, 2.4% of CareDx shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Summary

CareDx beats Ionis Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does CareDx compare to Praxis Precision Medicines?

CareDx (NASDAQ:CDNA) and Praxis Precision Medicines (NASDAQ:PRAX) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their dividends, risk, earnings, profitability, institutional ownership, valuation, media sentiment and analyst recommendations.

67.8% of Praxis Precision Medicines shares are owned by institutional investors. 2.4% of CareDx shares are owned by insiders. Comparatively, 3.0% of Praxis Precision Medicines shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

CareDx currently has a consensus price target of $47.75, suggesting a potential upside of 1.44%. Praxis Precision Medicines has a consensus price target of $573.05, suggesting a potential upside of 56.16%. Given Praxis Precision Medicines' stronger consensus rating and higher probable upside, analysts clearly believe Praxis Precision Medicines is more favorable than CareDx.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
CareDx
1 Sell rating(s)
3 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.43
Praxis Precision Medicines
2 Sell rating(s)
0 Hold rating(s)
16 Buy rating(s)
4 Strong Buy rating(s)
3.00

CareDx has a beta of 2.38, suggesting that its stock price is 138% more volatile than the broader market. Comparatively, Praxis Precision Medicines has a beta of 2.78, suggesting that its stock price is 178% more volatile than the broader market.

CareDx has higher revenue and earnings than Praxis Precision Medicines. Praxis Precision Medicines is trading at a lower price-to-earnings ratio than CareDx, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
CareDx$379.80M6.41-$21.35M$2.0722.74
Praxis Precision Medicines$8.55M1,198.31-$303.27M-$12.93N/A

CareDx has a net margin of 24.23% compared to Praxis Precision Medicines' net margin of 0.00%. CareDx's return on equity of 2.87% beat Praxis Precision Medicines' return on equity.

Company Net Margins Return on Equity Return on Assets
CareDx24.23% 2.87% 2.17%
Praxis Precision Medicines N/A -34.15%-32.42%

In the previous week, Praxis Precision Medicines had 6 more articles in the media than CareDx. MarketBeat recorded 22 mentions for Praxis Precision Medicines and 16 mentions for CareDx. CareDx's average media sentiment score of 0.70 beat Praxis Precision Medicines' score of 0.59 indicating that CareDx is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
CareDx
7 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Praxis Precision Medicines
7 Very Positive mention(s)
2 Positive mention(s)
9 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive

Summary

Praxis Precision Medicines beats CareDx on 9 of the 16 factors compared between the two stocks.

How does CareDx compare to Kymera Therapeutics?

Kymera Therapeutics (NASDAQ:KYMR) and CareDx (NASDAQ:CDNA) are both mid-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their profitability, valuation, earnings, analyst recommendations, risk, institutional ownership, media sentiment and dividends.

Kymera Therapeutics presently has a consensus price target of $125.65, suggesting a potential upside of 15.72%. CareDx has a consensus price target of $47.75, suggesting a potential upside of 1.44%. Given Kymera Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Kymera Therapeutics is more favorable than CareDx.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Kymera Therapeutics
1 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
0 Strong Buy rating(s)
2.83
CareDx
1 Sell rating(s)
3 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.43

Kymera Therapeutics has a beta of 1.95, suggesting that its stock price is 95% more volatile than the broader market. Comparatively, CareDx has a beta of 2.38, suggesting that its stock price is 138% more volatile than the broader market.

CareDx has higher revenue and earnings than Kymera Therapeutics. Kymera Therapeutics is trading at a lower price-to-earnings ratio than CareDx, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Kymera Therapeutics$39.21M230.26-$311.35M-$3.24N/A
CareDx$379.80M6.41-$21.35M$2.0722.74

CareDx has a net margin of 24.23% compared to Kymera Therapeutics' net margin of -285.33%. CareDx's return on equity of 2.87% beat Kymera Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Kymera Therapeutics-285.33% -21.22% -19.21%
CareDx 24.23%2.87%2.17%

In the previous week, Kymera Therapeutics had 13 more articles in the media than CareDx. MarketBeat recorded 29 mentions for Kymera Therapeutics and 16 mentions for CareDx. CareDx's average media sentiment score of 0.70 beat Kymera Therapeutics' score of -0.19 indicating that CareDx is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Kymera Therapeutics
2 Very Positive mention(s)
3 Positive mention(s)
5 Neutral mention(s)
4 Negative mention(s)
1 Very Negative mention(s)
Neutral
CareDx
7 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

CareDx beats Kymera Therapeutics on 9 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding CDNA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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CDNA vs. The Competition

MetricCareDxBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$2.42B$3.72B$7.06B$12.95B
Dividend YieldN/A3.76%2.58%10.20%
P/E Ratio274.659.13269.7524.74
Price / Sales6.411,274.20652.34108.60
Price / CashN/A44.9528.8937.44
Price / Book7.9917.6611.276.42
Net Income-$21.35M-$13.25M$3.45B$347.12M
7 Day Performance-1.63%5.36%3.56%2.48%
1 Month Performance65.10%-1.74%-0.58%-1.04%
1 Year Performance293.23%61.36%77.52%23.22%

CareDx Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
CDNA
CareDx
3.3737 of 5 stars
$47.07
+0.8%
$47.75
+1.4%
+290.1%$2.42B$379.80M274.65740
PTGX
Protagonist Therapeutics
1.4765 of 5 stars
$132.28
-3.2%
$123.00
-7.0%
+185.6%$8.79B$46.02MN/A120
SYRE
Spyre Therapeutics
2.2497 of 5 stars
$94.93
-3.5%
$101.42
+6.8%
+592.0%$8.65B$890KN/A73
IONS
Ionis Pharmaceuticals
3.7307 of 5 stars
$54.49
+5.3%
$94.65
+73.7%
+35.8%$8.60B$874.09MN/A1,402
PRAX
Praxis Precision Medicines
3.8121 of 5 stars
$305.51
-0.8%
$563.50
+84.4%
+685.3%$8.58B$8.55MN/A110

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This page (NASDAQ:CDNA) was last updated on 8/10/2026 by MarketBeat.com Staff.
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