Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Amgen Inc. stock logo
AMGN
Amgen
$269.98
+0.2%
$275.38
$211.71
$329.72
$144.81B0.582.82 million shs2.44 million shs
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
$65.42
+0.2%
$71.40
$64.63
$87.86
$81.45B0.197.48 million shs12.35 million shs
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$883.20
-0.8%
$949.30
$684.80
$998.33
$96.94B0.11491,077 shs505,575 shs
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$397.48
-0.1%
$412.09
$320.01
$448.40
$102.73B0.351.23 million shs682,467 shs
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Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Amgen Inc. stock logo
AMGN
Amgen
-1.33%+2.52%-4.40%-13.60%+12.81%
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
-2.70%-1.35%-9.86%-17.92%-22.06%
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
-1.75%-0.37%-7.56%-5.25%+14.48%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
-0.76%+1.07%-4.96%-7.55%+23.01%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Amgen Inc. stock logo
AMGN
Amgen
4.6689 of 5 stars
2.34.04.23.91.31.72.5
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
4.9992 of 5 stars
4.25.04.24.12.92.53.1
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
4.4595 of 5 stars
3.44.00.02.32.62.51.9
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
4.2549 of 5 stars
2.23.00.03.33.22.52.5

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Amgen Inc. stock logo
AMGN
Amgen
2.53
Moderate Buy$296.959.99% Upside
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
2.31
Hold$83.8728.20% Upside
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
2.70
Moderate Buy$977.7710.71% Upside
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
2.48
Hold$429.458.04% Upside

Current Analyst Ratings

Latest AMGN, GILD, VRTX, and REGN Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/26/2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
Morgan Stanley
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetEqual Weight ➝ Equal Weight$80.00 ➝ $78.00
4/26/2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
TD Cowen
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Lower Price TargetBuy ➝ Buy$90.00 ➝ $85.00
4/26/2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
Royal Bank of Canada
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Lower Price TargetSector Perform ➝ Sector Perform$76.00 ➝ $74.00
4/26/2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
Needham & Company LLC
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Reiterated RatingHold
4/24/2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
HSBC
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UpgradeReduce ➝ Hold$69.00
4/24/2024
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
TD Cowen
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$1,020.00 ➝ $1,030.00
4/19/2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
Oppenheimer
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform ➝ Outperform$105.00
4/18/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Guggenheim
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Boost Price TargetBuy ➝ Buy$445.00 ➝ $450.00
4/17/2024
Amgen Inc. stock logo
AMGN
Amgen
UBS Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetNeutral ➝ Neutral$314.00 ➝ $284.00
4/17/2024
Amgen Inc. stock logo
AMGN
Amgen
TD Cowen
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$370.00 ➝ $360.00
4/17/2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
UBS Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetNeutral ➝ Neutral$81.00 ➝ $75.00
(Data available from 4/26/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Amgen Inc. stock logo
AMGN
Amgen
$28.19B5.14$26.06 per share10.36$11.65 per share23.17
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
$27.12B3.00$8.72 per share7.50$18.26 per share3.58
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$13.12B7.39$42.16 per share20.95$236.63 per share3.73
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$9.87B10.41$14.54 per share27.34$68.22 per share5.83

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Amgen Inc. stock logo
AMGN
Amgen
$6.72B$12.4921.6212.872.5423.83%154.27%10.95%5/2/2024 (Confirmed)
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
$5.67B$4.5014.549.001.2020.89%38.85%13.60%8/1/2024 (Estimated)
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$3.95B$34.7525.4221.882.6030.14%17.61%13.76%5/2/2024 (Confirmed)
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.62B$13.8928.6224.631.8936.68%21.91%16.73%5/6/2024 (Confirmed)

Latest AMGN, GILD, VRTX, and REGN Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/6/2024N/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.61N/A-$3.61N/AN/AN/A  
5/2/2024N/A
Amgen Inc. stock logo
AMGN
Amgen
$3.82N/A-$3.82N/AN/AN/A  
5/2/2024N/A
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$8.07N/A-$8.07N/AN/AN/A  
4/25/2024Q1 2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
-$1.49-$1.32+$0.17$0.70$6.36 billion$6.69 billion    
2/6/2024Q4 23
Amgen Inc. stock logo
AMGN
Amgen
$4.66$4.71+$0.05$8.00$8.13 billion$8.20 billion    
2/6/2024Q4 23
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
$1.76$1.72-$0.04$2.30$7.10 billion$7.12 billion    
2/5/2024Q4 23
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.85$4.20+$0.35$3.43$2.50 billion$2.52 billion    
2/2/202412/31/2023
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$10.73$11.86+$1.13$10.17$3.29 billion$3.43 billion    

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Amgen Inc. stock logo
AMGN
Amgen
$9.003.33%+10.01%72.06%12 Years
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
$3.084.71%+3.32%68.44%9 Years
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
N/AN/AN/AN/AN/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
N/AN/AN/AN/AN/A

Latest AMGN, GILD, VRTX, and REGN Dividends

AnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date
3/6/2024
Amgen Inc. stock logo
AMGN
Amgen
quarterly$2.253.25%5/16/20245/17/20246/7/2024
2/1/2024
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
Quarterly$0.774.14%3/14/20243/15/20243/28/2024
(Data available from 1/1/2013 forward)

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Amgen Inc. stock logo
AMGN
Amgen
10.14
1.65
1.13
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
1.08
1.43
1.27
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
0.10
5.69
4.94
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
0.02
3.99
3.78

Ownership

Institutional Ownership

CompanyInstitutional Ownership
Amgen Inc. stock logo
AMGN
Amgen
76.50%
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
83.67%
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
83.31%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
90.96%

Insider Ownership

CompanyInsider Ownership
Amgen Inc. stock logo
AMGN
Amgen
0.46%
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
0.16%
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
8.83%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
0.20%

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
Amgen Inc. stock logo
AMGN
Amgen
26,700536.38 million533.91 millionOptionable
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
18,0001.25 billion1.24 billionOptionable
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
13,450109.76 million100.07 millionOptionable
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
5,400258.46 million257.94 millionOptionable

AMGN, GILD, VRTX, and REGN Headlines

SourceHeadline
Pioneer Institute study finds IRA discourages non-opioid drug innovationPioneer Institute study finds IRA discourages non-opioid drug innovation
pharmaceutical-technology.com - April 26 at 4:37 PM
ALPINE IMMUNE INVESTOR ALERT by the Former Attorney General of Louisiana: Kahn Swick & Foti, LLC Investigates Adequacy of Price and Process in Proposed Sale of Alpine Immune Sciences, Inc. - ALPNALPINE IMMUNE INVESTOR ALERT by the Former Attorney General of Louisiana: Kahn Swick & Foti, LLC Investigates Adequacy of Price and Process in Proposed Sale of Alpine Immune Sciences, Inc. - ALPN
businesswire.com - April 26 at 4:13 PM
Meritage Portfolio Management Purchases 15,006 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Meritage Portfolio Management Purchases 15,006 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 26 at 2:53 PM
The Zacks Analyst Blog Highlights Biogen, Bristol Myers Squibb, Incyte and Vertex PharmaceuticalsThe Zacks Analyst Blog Highlights Biogen, Bristol Myers Squibb, Incyte and Vertex Pharmaceuticals
finance.yahoo.com - April 26 at 10:46 AM
Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Given Consensus Rating of "Hold" by BrokeragesVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Given Consensus Rating of "Hold" by Brokerages
americanbankingnews.com - April 26 at 1:38 AM
Bank Julius Baer & Co. Ltd Zurich Purchases 18,002 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Bank Julius Baer & Co. Ltd Zurich Purchases 18,002 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 25 at 8:34 PM
Vertex Pharmaceuticals (VRTX) Falls More Steeply Than Broader Market: What Investors Need to KnowVertex Pharmaceuticals (VRTX) Falls More Steeply Than Broader Market: What Investors Need to Know
zacks.com - April 25 at 6:56 PM
2 Fantastic Growth Stocks to Buy Right Now2 Fantastic Growth Stocks to Buy Right Now
fool.com - April 25 at 9:45 AM
Yousif Capital Management LLC Sells 2,576 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Yousif Capital Management LLC Sells 2,576 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 24 at 4:00 PM
F M Investments LLC Buys Shares of 4,129 Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)F M Investments LLC Buys Shares of 4,129 Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 23 at 10:08 PM
Vertex hops on to TreeFrog platform to aid diabetes bidVertex hops on to TreeFrog platform to aid diabetes bid
thepharmaletter.com - April 23 at 10:50 AM
Vertex (VRTX), TreeFrog Sign Deal for Diabetes Cell TherapiesVertex (VRTX), TreeFrog Sign Deal for Diabetes Cell Therapies
zacks.com - April 23 at 9:10 AM
Vertex Pharmaceuticals Just Made 2 Big Moves. Is the Stock a Buy?Vertex Pharmaceuticals Just Made 2 Big Moves. Is the Stock a Buy?
fool.com - April 23 at 6:05 AM
VERTEX AND TREEFROG THERAPEUTICS ANNOUNCE LICENSING AGREEMENT AND COLLABORATION TO OPTIMIZE PRODUCTION OF VERTEXS CELL THERAPIES FOR TYPE 1 DIABETESVERTEX AND TREEFROG THERAPEUTICS ANNOUNCE LICENSING AGREEMENT AND COLLABORATION TO OPTIMIZE PRODUCTION OF VERTEX'S CELL THERAPIES FOR TYPE 1 DIABETES
prnewswire.com - April 23 at 12:45 AM
Illinois Municipal Retirement Fund Buys 3,033 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Illinois Municipal Retirement Fund Buys 3,033 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 22 at 9:59 PM
If Youd Invested $10,000 in Vertex Pharmaceuticals 5 Years Ago, Heres How Much Youd Have TodayIf You'd Invested $10,000 in Vertex Pharmaceuticals 5 Years Ago, Here's How Much You'd Have Today
fool.com - April 22 at 7:16 AM
Looking for Once-in-a-Generation Investment Opportunities? Here Are 3 Magnificent Stocks to Buy Right NowLooking for Once-in-a-Generation Investment Opportunities? Here Are 3 Magnificent Stocks to Buy Right Now
fool.com - April 22 at 5:52 AM
Q3 2025 EPS Estimates for Vertex Pharmaceuticals Incorporated Lowered by Zacks Research (NASDAQ:VRTX)Q3 2025 EPS Estimates for Vertex Pharmaceuticals Incorporated Lowered by Zacks Research (NASDAQ:VRTX)
americanbankingnews.com - April 22 at 2:18 AM
Ardevora Asset Management LLP Has $11.54 Million Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Ardevora Asset Management LLP Has $11.54 Million Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 21 at 8:52 PM
Lindbrook Capital LLC Grows Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Lindbrook Capital LLC Grows Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 20 at 1:16 PM
2 Everlasting Big Pharma Stocks to Buy Today and Hold Forever2 Everlasting Big Pharma Stocks to Buy Today and Hold Forever
fool.com - April 20 at 9:45 AM
3 Relatively Safe Growth Stocks You Can Buy and Hold3 Relatively Safe Growth Stocks You Can Buy and Hold
fool.com - April 20 at 6:48 AM
3 Biotech Stocks Set to Double by 20283 Biotech Stocks Set to Double by 2028
investorplace.com - April 20 at 6:15 AM
Vertex Pharmaceuticals (NASDAQ:VRTX) PT Raised to $450.00Vertex Pharmaceuticals (NASDAQ:VRTX) PT Raised to $450.00
americanbankingnews.com - April 20 at 3:50 AM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

All Headlines

Company Descriptions

Amgen logo

Amgen

NASDAQ:AMGN
Amgen Inc. discovers, develops, manufactures, and delivers human therapeutics worldwide. The company's principal products include Enbrel to treat plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis; Otezla for the treatment of adult patients with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's disease; Prolia to treat postmenopausal women with osteoporosis; XGEVA for skeletal-related events prevention; Repatha, which reduces the risks of myocardial infarction, stroke, and coronary revascularization; Nplate for the treatment of patients with immune thrombocytopenia; KYPROLIS to treat patients with relapsed or refractory multiple myeloma; Aranesp to treat a lower-than-normal number of red blood cells and anemia; EVENITY for the treatment of osteoporosis in postmenopausal for men and women; Vectibix to treat patients with wild-type RAS metastatic colorectal cancer; BLINCYTO for the treatment of patients with acute lymphoblastic leukemia; TEPEZZA to treat thyroid eye disease; and KRYSTEXXA for the treatment of chronic refractory gout. It also markets other products, including Neulasta, MVASI, AMJEVITA/AMGEVITA, TEZSPIRE, Parsabiv, Aimovig, LUMAKRAS/LUMYKRAS, EPOGEN, KANJINTI, TAVNEOS, RAVICTI, UPLIZNA and PROCYSBI. The company serves healthcare providers, including physicians or their clinics, dialysis centers, hospitals, and pharmacies. It distributes its products through pharmaceutical wholesale distributors, as well as direct-to-consumer channels. The company has collaboration agreements with AstraZeneca plc for the development and commercialization of TEZSPIRE; Novartis Pharma AG to develop and commercialize Aimovig; UCB for the development and commercialization of EVENITY; Kyowa Kirin Co., Ltd. for rocatinlimab development and commercialization; and BeiGene, Ltd. for oncology products expansion and development. Amgen Inc. was incorporated in 1980 and is headquartered in Thousand Oaks, California.
Gilead Sciences logo

Gilead Sciences

NASDAQ:GILD
Gilead Sciences, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines in the areas of unmet medical need in the United States, Europe, and internationally. The company provides Biktarvy, Genvoya, Descovy, Odefsey, Truvada, Complera/ Eviplera, Stribild, Sunlencs, and Atripla products for the treatment of HIV/AIDS; Veklury, an injection for intravenous use, for the treatment of COVID-19; and Epclusa, Harvoni, Vemlidy, and Viread for the treatment of viral hepatitis. It also offers Yescarta, Tecartus, and Trodelvy products for the treatment of oncology; Letairis, an oral formulation for the treatment of pulmonary arterial hypertension; and AmBisome, a liposomal formulation for the treatment of serious invasive fungal infections. The company has collaboration agreements with Arcus Biosciences, Inc.; Merck Sharp & Dohme Corp.; Pionyr Immunotherapeutics Inc.; Tizona Therapeutics, Inc.; Galapagos NV; Janssen Sciences Ireland Unlimited Company; Japan Tobacco, Inc.; Dragonfly Therapeutics, Inc.; Arcellx, Inc.; Everest Medicines; Merck & Co, Inc.; Tentarix Biotherapeutics Inc.; and Assembly Biosciences, Inc. It also has research collaboration, option, and license agreement with Merus N.V. for the discovery of novel dual tumor-associated antigens (TAA) targeting trispecific antibodies. The company was incorporated in 1987 and is headquartered in Foster City, California.
Regeneron Pharmaceuticals logo

Regeneron Pharmaceuticals

NASDAQ:REGN
Regeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines for treating various diseases worldwide. The company's products include EYLEA injection to treat wet age-related macular degeneration and diabetic macular edema; myopic choroidal neovascularization; diabetic retinopathy; neovascular glaucoma; and retinopathy of prematurity. It also provides Dupixent injection to treat atopic dermatitis and asthma in adults and pediatrics; Libtayo injection to treat metastatic or locally advanced cutaneous squamous cell carcinoma; Praluent injection for heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in adults; REGEN-COV for covid-19; and Kevzara solution for treating rheumatoid arthritis in adults. In addition, the company offers Inmazeb injection for infection caused by Zaire ebolavirus; ARCALYST injection for cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome and muckle-wells syndrome; and ZALTRAP injection for intravenous infusion to treat metastatic colorectal cancer; and develops product candidates for treating patients with eye, allergic and inflammatory, cardiovascular and metabolic, infectious, and rare diseases; and cancer, pain, and hematologic conditions. The company was incorporated in 1988 and is headquartered in Tarrytown, New York.
Vertex Pharmaceuticals logo

Vertex Pharmaceuticals

NASDAQ:VRTX
Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.