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Vertex Pharmaceuticals (VRTX) Stock Forecast & Price Target

Vertex Pharmaceuticals logo
$547.03 -0.86 (-0.16%)
Closing price 11/11/2026 04:00 PM Eastern
Extended Trading
$544.34 -2.69 (-0.49%)
As of 11/11/2026 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Vertex Pharmaceuticals - Analysts' Recommendations and Stock Price Forecast (2026)

Consensus Rating

Sell
0
Hold
2
Buy
26

Based on 28 Wall Street analysts who have issued ratings for Vertex Pharmaceuticals in the last 12 months, the stock has a consensus rating of "Moderate Buy." Out of the 28 analysts, 2 have given a hold rating, 25 have given a buy rating, and 1 has given a strong buy rating for VRTX.

Consensus Price Target

$596.44
9.03% Upside
According to the 28 analysts' twelve-month price targets for Vertex Pharmaceuticals, the average price target is $596.44. The highest price target for VRTX is $725.00, while the lowest price target for VRTX is $442.00. The average price target represents a forecasted upside of 9.03% from the current price of $547.03.
MarketBeat calculates consensus analyst ratings for stocks using the most recent rating from each Wall Street analyst that has rated a stock within the last twelve months. Each analyst's rating is normalized to a standardized rating score of 1 (sell), 2 (hold), 3 (buy) or 4 (strong buy). Analyst consensus ratings scores are calculated using the mean average of the number of normalized sell, hold, buy and strong buy ratings from Wall Street analysts. Each stock's consensus analyst rating is derived from its calculated consensus ratings score (0 to .5 = Strong Sell, .5 to 1 = Sell, 1 to 1.5 = Reduce, 1.5 to 2.5 = Hold, 2.5 to 3.0 = Moderate Buy, 3.0 to 3.5 = Buy, >3.5 = Strong Buy). MarketBeat's consensus price targets are a mean average of the most recent available price targets set by each analyst that has set a price target for the stock in the last twelve months. MarketBeat's consensus ratings and consensus price targets may differ from those calculated by other firms due to differences in methodology and available data.
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VRTX Analyst Ratings Over Time

TypeCurrent Forecast
11/12/25 to 11/12/26
1 Month Ago
10/13/25 to 10/13/26
3 Months Ago
8/14/25 to 8/14/26
1 Year Ago
11/12/24 to 11/12/25
Strong Buy
1 Strong Buy rating(s)
1 Strong Buy rating(s)
1 Strong Buy rating(s)
1 Strong Buy rating(s)
Buy
25 Buy rating(s)
24 Buy rating(s)
24 Buy rating(s)
16 Buy rating(s)
Hold
2 Hold rating(s)
3 Hold rating(s)
4 Hold rating(s)
13 Hold rating(s)
Sell
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
Consensus Price Target$596.44$579.81$560.11$492.71
Forecasted Upside9.03% Upside19.50% Upside10.75% Upside13.48% Upside
Consensus RatingModerate BuyModerate BuyModerate BuyModerate Buy

VRTX Analyst Recommendations By Month

The chart below shows how a company's ratings by analysts have changed over time. Each bar represents the previous year of ratings for that month. Within each bar, the sell ratings are shown in red, the hold ratings are shown in yellow, the buy ratings are shown in green, and the strong buy ratings are shown in dark green.
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VRTX Price Targets by Month

The chart below shows how a company's share price and consensus price target have changed over time. The dark blue line represents the company's actual price. The lighter blue line represents the stock's consensus price target. The even lighter blue range in the background of the two lines represents the low price target and the high price target for each stock.
Skip Chart and View Analyst Price Target HistorySkip Chart & View Price History Table

Vertex Pharmaceuticals Stock vs. The Competition

TypeVertex PharmaceuticalsHealthcare CompaniesBroader Market
Consensus Rating Score
2.96
2.32
2.52
Consensus RatingModerate BuyHoldModerate Buy
Predicted Upside9.03% Upside110.66% Upside13.64% Upside
News Sentiment Rating
Positive News

See Recent VRTX News
Positive News
Positive News
Report Date
0 Results
DateBrokerageAnalystActionRatingPrice TargetReport Date
Upside/Downside
Details
11/9/2026
Weiss Ratings logo
Weiss Ratings
2 of 5 stars
 DowngradeBuy (B) ➝ Buy (B-)
11/4/2026
Barclays PLC logo
Barclays
3 of 5 stars
Eliana Merle
Not Rated
Boost TargetOverweight$617.00 ➝ $626.00+14.25%
11/3/2026
Jessica Fye
Jessica Fye
4 of 5 stars
Boost TargetOverweight$560.00 ➝ $570.00+6.02%
11/3/2026Boost TargetSector Outperform$558.00 ➝ $660.00+23.76%
11/3/2026Lower TargetOverweight$665.00 ➝ $660.00+23.76%
11/3/2026Boost TargetBuy$654.00 ➝ $725.00+35.95%
11/3/2026Boost TargetBuy$615.00 ➝ $640.00+19.45%
11/3/2026Boost TargetBuy$550.00 ➝ $575.00+7.38%
11/3/2026Boost TargetOutperform$576.00 ➝ $600.00+10.90%
11/3/2026Boost TargetOverweight$550.00 ➝ $650.00+20.15%
11/3/2026Boost TargetHold$500.00 ➝ $563.00+1.78%
11/3/2026Boost TargetOverweight$595.00 ➝ $619.00+11.90%
9/23/2026 Boost TargetBuy$633.00 ➝ $640.00+25.46%
9/21/2026 Initiated CoverageOutperform$594.00+17.18%
9/2/2026 Boost TargetOutperform$535.00 ➝ $600.00+17.62%
8/11/2026 Boost TargetBuy$555.00 ➝ $556.00+8.99%
8/5/2026Boost TargetBuy$560.00 ➝ $565.00+15.85%
8/5/2026 Boost TargetBuy$570.00 ➝ $580.00+13.70%
8/4/2026Boost TargetHold$436.00 ➝ $442.00-6.10%
7/29/2026UpgradeStrong-Buy
3/19/2026 Boost TargetBuy$475.00 ➝ $520.00+1.96%
3/18/2026UpgradeHold ➝ Buy$575.00+24.33%
3/10/2026Boost TargetBuy$571.00 ➝ $598.00+18.47%
3/10/2026Boost TargetBuy$575.00 ➝ $585.00+16.38%
3/10/2026Boost TargetOutperform$540.00 ➝ $600.00+30.19%
3/10/2026Boost TargetBuy$591.00 ➝ $641.00+39.08%
3/2/2026 Boost TargetOutperform$530.00 ➝ $600.00+17.64%
1/6/2026UpgradePeer Perform ➝ Outperform$548.00+22.10%
9/2/2025Initiated CoverageMarket Perform
8/29/2025 Lower TargetBuy$600.00 ➝ $480.00-5.90%
8/6/2025Lower TargetBuy$558.00 ➝ $546.00+40.91%
5/23/2025DowngradeStrong-Buy ➝ Hold
5/6/2025 Reiterated RatingOutperform
5/6/2025Reiterated RatingHold
1/27/2025Lower TargetOverweight$535.00 ➝ $533.00+20.72%

Analyst ratings data on MarketBeat is provided by Benzinga and other data providers. This page was last refreshed on Thursday at 01:35 AM ET.


Should I Buy Vertex Pharmaceuticals Stock? VRTX Pros and Cons Explained

These pros and cons were generated based on recent news and financial data from MarketBeat in order to provide readers with the fastest and most accurate insights. They were last updated on Wednesday, November 11, 2026. Please send any questions or comments about these Vertex Pharmaceuticals pros and cons to contact@marketbeat.com.

Vertex Pharmaceuticals
Bull Case

green Wall Street bull icon

Here are some ways that investors could benefit from investing in Vertex Pharmaceuticals Incorporated:

  • Vertex Pharmaceuticals Incorporated is trading at $547.03, which is below the consensus price target of $596.44 set by sell-side analysts who maintain a Moderate Buy rating, suggesting potential for capital appreciation as the stock has already risen significantly from its 52-week low of $412.27.
  • The company demonstrated strong financial performance in the most recent quarter with revenue of $3.44 billion, representing an 11.8% year-over-year increase, and a net margin of 30.70%, indicating robust profitability and effective cost management despite rising operational expenses.
  • Vertex Pharmaceuticals Incorporated maintains a dominant market position in cystic fibrosis therapies with its flagship product Trikafta/Kaftrio, which targets the underlying protein defect, providing a stable and high-margin revenue base that supports the company's valuation and growth trajectory.
  • Institutional investor confidence remains high, with 90.96% of the company's stock owned by institutional investors and hedge funds, and recent filings show significant new positions being acquired by major firms like BlackRock and Bank of America, signaling strong long-term interest in the company's stability.
  • The company is successfully diversifying its portfolio beyond cystic fibrosis by expanding into gene therapies and endocrinology, with partnerships such as the development of Casgevy for sickle cell disease and the acquisition of Crinetics, which balances growth opportunities with the integration of new therapeutic areas.

Vertex Pharmaceuticals
Bear Case

red Wall Street bear icon

Investors should be bearish about investing in Vertex Pharmaceuticals Incorporated for these reasons:

  • Vertex Pharmaceuticals Incorporated missed its earnings per share estimate in the most recent quarter, reporting $4.76 compared to the consensus of $4.82, which may indicate challenges in maintaining the high growth rates expected by the market despite strong revenue figures.
  • There is a notable trend of insider selling, with multiple executives including the CMO and several EVPs selling significant numbers of shares in the first half of 2026, which can be interpreted as a lack of confidence in the stock's short-term upside or a desire to lock in gains.
  • The company's price-to-earnings ratio of 35.20 is relatively high, reflecting a premium valuation that may be difficult to sustain if growth slows or if the market becomes more risk-averse, particularly given that costs are now outgrowing sales according to recent analysis.
  • Vertex Pharmaceuticals Incorporated faces integration risks from its recent acquisitions and partnerships, such as the Crinetics deal, which could divert management attention and resources away from the core cystic fibrosis business, potentially impacting operational efficiency and innovation timelines.
  • The stock has experienced volatility, with a 52-week range from $412.27 to $568.67, and recent short interest data shows fluctuations in shares shorted, indicating that some investors are betting against the stock, which could lead to further price declines if negative sentiment persists.

VRTX Forecast - Frequently Asked Questions

According to the research reports of 28 Wall Street equities research analysts, the average twelve-month stock price forecast for Vertex Pharmaceuticals is $596.44, with a high forecast of $725.00 and a low forecast of $442.00.

28 Wall Street research analysts have issued "buy," "hold," and "sell" ratings for Vertex Pharmaceuticals in the last year. There are currently 2 hold ratings, 25 buy ratings and 1 strong buy rating for the stock. The consensus among Wall Street research analysts is that investors should "moderate buy" VRTX shares.

According to analysts, Vertex Pharmaceuticals's stock has a predicted upside of 9.03% based on their 12-month stock forecasts.

Over the previous 90 days, Vertex Pharmaceuticals's stock had 3 downgrades and 2 upgrades by analysts.

Analysts like Vertex Pharmaceuticals more than other "healthcare" companies. The consensus rating for Vertex Pharmaceuticals is Moderate Buy while the average consensus rating for "healthcare" companies is Hold. Learn more on how VRTX compares to other companies.


MarketBeat monitors more than a dozen sources for Vertex Pharmaceuticals analyst ratings, with the most recent rating issued on 11/9/2026.
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