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Vertex Pharmaceuticals (VRTX) Stock Forecast & Price Target

Vertex Pharmaceuticals logo
$546.12 0.00 (0.00%)
As of 09/4/2026 04:00 PM Eastern

Vertex Pharmaceuticals - Analysts' Recommendations and Stock Price Forecast (2026)

Consensus Rating

Sell
0
Hold
2
Buy
21

Based on 23 Wall Street analysts who have issued ratings for Vertex Pharmaceuticals in the last 12 months, the stock has a consensus rating of "Moderate Buy." Out of the 23 analysts, 2 have given a hold rating, 20 have given a buy rating, and 1 has given a strong buy rating for VRTX.

Consensus Price Target

$569.52
4.29% Upside
According to the 23 analysts' twelve-month price targets for Vertex Pharmaceuticals, the average price target is $569.52. The highest price target for VRTX is $665.00, while the lowest price target for VRTX is $442.00. The average price target represents a forecasted upside of 4.29% from the current price of $546.12.
MarketBeat calculates consensus analyst ratings for stocks using the most recent rating from each Wall Street analyst that has rated a stock within the last twelve months. Each analyst's rating is normalized to a standardized rating score of 1 (sell), 2 (hold), 3 (buy) or 4 (strong buy). Analyst consensus ratings scores are calculated using the mean average of the number of normalized sell, hold, buy and strong buy ratings from Wall Street analysts. Each stock's consensus analyst rating is derived from its calculated consensus ratings score (0 to .5 = Strong Sell, .5 to 1 = Sell, 1 to 1.5 = Reduce, 1.5 to 2.5 = Hold, 2.5 to 3.0 = Moderate Buy, 3.0 to 3.5 = Buy, >3.5 = Strong Buy). MarketBeat's consensus price targets are a mean average of the most recent available price targets set by each analyst that has set a price target for the stock in the last twelve months. MarketBeat's consensus ratings and consensus price targets may differ from those calculated by other firms due to differences in methodology and available data.
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VRTX Analyst Ratings Over Time

TypeCurrent Forecast
9/7/25 to 9/7/26
1 Month Ago
8/8/25 to 8/8/26
3 Months Ago
6/9/25 to 6/9/26
1 Year Ago
9/7/24 to 9/7/25
Strong Buy
1 Strong Buy rating(s)
1 Strong Buy rating(s)
0 Strong Buy rating(s)
1 Strong Buy rating(s)
Buy
20 Buy rating(s)
20 Buy rating(s)
22 Buy rating(s)
13 Buy rating(s)
Hold
2 Hold rating(s)
3 Hold rating(s)
3 Hold rating(s)
12 Hold rating(s)
Sell
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
Consensus Price Target$569.52$563.50$555.91$497.10
Forecasted Upside4.29% Upside13.59% Upside24.71% Upside25.49% Upside
Consensus RatingModerate BuyModerate BuyModerate BuyModerate Buy

VRTX Analyst Recommendations By Month

The chart below shows how a company's ratings by analysts have changed over time. Each bar represents the previous year of ratings for that month. Within each bar, the sell ratings are shown in red, the hold ratings are shown in yellow, the buy ratings are shown in green, and the strong buy ratings are shown in dark green.
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VRTX Price Targets by Month

The chart below shows how a company's share price and consensus price target have changed over time. The dark blue line represents the company's actual price. The lighter blue line represents the stock's consensus price target. The even lighter blue range in the background of the two lines represents the low price target and the high price target for each stock.
Skip Chart and View Analyst Price Target HistorySkip Chart & View Price History Table

Vertex Pharmaceuticals Stock vs. The Competition

TypeVertex PharmaceuticalsHealthcare CompaniesBroader Market
Consensus Rating Score
2.96
2.30
2.53
Consensus RatingModerate BuyHoldModerate Buy
Predicted Upside4.29% Upside928.71% Upside14.03% Upside
News Sentiment Rating
Positive News

See Recent VRTX News
Positive News
Positive News
DateBrokerageAnalystActionRatingPrice TargetReport Date
Upside/Downside
Details
9/1/2026
Morgan Stanley logo
Morgan Stanley
3 of 5 stars
Terence Flynn
Terence Flynn
5 of 5 stars
Initiated CoverageOverweight$665.00+21.43%
9/1/2026 Set Target$653.00+19.92%
8/25/2026
Weiss Ratings logo
Weiss Ratings
5 of 5 stars
 DowngradeBuy (B)Buy (B-)
8/5/2026Boost TargetBuy$560.00 ➝ $565.00+15.85%
8/5/2026Boost TargetOverweight$615.00 ➝ $617.00+28.89%
8/4/2026Boost TargetBuy$525.00 ➝ $550.00+16.84%
8/4/2026 Set Target$500.00+2.81%
8/4/2026Boost TargetHold$436.00 ➝ $442.00-6.10%
8/4/2026Boost TargetOverweight$590.00 ➝ $595.00+26.40%
7/29/2026UpgradeStrong-Buy
7/13/2026Boost TargetBuy$545.00 ➝ $585.00+21.41%
7/7/2026Boost TargetOutperform$543.00 ➝ $570.00+7.63%
3/18/2026UpgradeHoldBuy$575.00+24.33%
3/10/2026Boost TargetBuy$571.00 ➝ $598.00+18.47%
3/10/2026Boost TargetBuy$575.00 ➝ $585.00+16.38%
3/10/2026Initiated CoverageBuy$580.00+25.85%
3/10/2026Boost TargetOutperform$540.00 ➝ $600.00+30.19%
3/10/2026Boost TargetBuy$591.00 ➝ $641.00+39.08%
2/13/2026Boost TargetOutperform$495.00 ➝ $558.00+12.34%
1/23/2026Boost TargetOutperform$475.00 ➝ $530.00+13.41%
1/6/2026UpgradePeer PerformOutperform$548.00+22.10%
12/29/2025Boost TargetOutperform$456.00 ➝ $525.00+13.42%
12/10/2025Boost TargetOverweight$460.00 ➝ $515.00+15.74%
10/8/2025Boost TargetOverweight$517.00 ➝ $530.00+26.34%
9/2/2025Initiated CoverageMarket Perform
8/6/2025Lower TargetBuy$558.00 ➝ $546.00+40.91%
8/5/2025Set TargetOutperform$557.00 ➝ $530.00+12.22%
5/23/2025DowngradeStrong-BuyHold
5/6/2025 Reiterated RatingOutperform
5/6/2025Reiterated RatingHold
1/27/2025Lower TargetOverweight$535.00 ➝ $533.00+20.72%

Analyst ratings data on MarketBeat is provided by Benzinga and other data providers. This page was last refreshed on Monday at 08:26 AM ET.


Should I Buy Vertex Pharmaceuticals Stock? VRTX Pros and Cons Explained

These pros and cons were generated based on recent news and financial data from MarketBeat in order to provide readers with the fastest and most accurate insights. They were last updated on Saturday, September 5, 2026. Please send any questions or comments about these Vertex Pharmaceuticals pros and cons to contact@marketbeat.com.

Vertex Pharmaceuticals
Bull Case

green Wall Street bull icon

Here are some ways that investors could benefit from investing in Vertex Pharmaceuticals Incorporated:

  • Vertex Pharmaceuticals Incorporated completed the acquisition of Crinetics Pharmaceuticals on September 1, 2026, adding a rare endocrine growth platform that includes therapies with combined peak annual revenue potential of more than $5 billion, which significantly diversifies the company's portfolio beyond cystic fibrosis.
  • The stock is currently trading at $546.12, which is near its 52-week high of $560.25, reflecting strong recent momentum and a 14.4% increase since the last earnings report, indicating high investor confidence in the company's recent strategic moves.
  • Vertex Pharmaceuticals Incorporated reported revenue of $3.33 billion for the most recent quarter, beating analyst expectations of $3.23 billion and showing a 12.5% year-over-year increase, which demonstrates robust commercial execution and demand for its marketed products.
  • The company maintains a low beta of 0.32, meaning its stock price is significantly less volatile than the broader market, which can provide a more stable investment profile for risk-averse investors seeking exposure to the biotechnology sector.
  • Analysts have maintained a consensus rating of Moderate Buy with an average price target of $569.52, suggesting that the current market price still offers potential upside as institutions like NEOS Investment Management LLC continue to increase their positions in the stock.

Vertex Pharmaceuticals
Bear Case

red Wall Street bear icon

Investors should be bearish about investing in Vertex Pharmaceuticals Incorporated for these reasons:

  • Vertex Pharmaceuticals Incorporated recently missed its earnings per share consensus estimate by $0.01 in the latest quarter, reporting $4.73 against an expected $4.74, which may signal that the company is facing challenges in maintaining its previous pace of profit growth.
  • The stock is trading at a price-to-earnings ratio of 31.79, which is a premium valuation that leaves little room for error if future revenue growth slows or if the integration of the newly acquired Crinetics Pharmaceuticals does not yield the expected synergies.
  • Insiders have been actively selling shares, with executives such as EVP Ourania Tatsis and EVP Duncan McKechnie selling a combined 2,941 shares in July 2026, which can be interpreted as a lack of confidence from those with the most knowledge of the company's internal operations.
  • The company does not pay a dividend, with a yield of 0.00%, which may be a drawback for income-focused investors who prefer regular cash flow from their biotechnology holdings rather than relying solely on capital appreciation.
  • Vertex Pharmaceuticals Incorporated has underperformed the broader biotechnology industry over the past year, suggesting that its relative growth rate may be lagging behind its peers despite its strong absolute performance.

VRTX Forecast - Frequently Asked Questions

According to the research reports of 23 Wall Street equities research analysts, the average twelve-month stock price forecast for Vertex Pharmaceuticals is $569.52, with a high forecast of $665.00 and a low forecast of $442.00.

23 Wall Street equities research analysts have issued "buy," "hold," and "sell" ratings for Vertex Pharmaceuticals in the last twelve months. There are currently 2 hold ratings, 20 buy ratings and 1 strong buy rating for the stock. The consensus among Wall Street equities research analysts is that investors should "moderate buy" VRTX shares.

According to analysts, Vertex Pharmaceuticals's stock has a predicted upside of 4.29% based on their 12-month stock forecasts.

Over the previous 90 days, Vertex Pharmaceuticals's stock had 3 upgrades and 2 downgrades by analysts.

Analysts like Vertex Pharmaceuticals more than other "healthcare" companies. The consensus rating for Vertex Pharmaceuticals is Moderate Buy while the average consensus rating for "healthcare" companies is Hold. Learn more on how VRTX compares to other companies.


MarketBeat monitors more than a dozen sources for Vertex Pharmaceuticals analyst ratings, with the most recent rating issued on 9/1/2026.
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