Compare Stocks

Comparative Price Performance Over Time

Compare Stocks - Price & Volume

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Incyte Co. stock logo
INCY
Incyte
$51.68
+1.0%
$56.78
$50.27
$75.74
$11.60B0.651.61 million shs1.56 million shs
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
$120.75
+3.9%
$123.69
$63.44
$135.51
$8.10B1.67586,261 shs480,722 shs
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
$5.00
+4.6%
$5.56
$4.70
$11.68
$191.31M0.78277,174 shs190,352 shs
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$397.48
-0.1%
$411.60
$320.01
$448.40
$102.73B0.35909,553 shs682,467 shs
Beginners Guide To Retirement Stocks Cover

Click the link below and we'll send you MarketBeat's list of seven best retirement stocks and why they should be in your portfolio.

Get This Free Report

Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Incyte Co. stock logo
INCY
Incyte
0.00%-1.28%-9.29%-14.78%-29.72%
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
0.00%+11.63%-9.21%+9.64%+49.81%
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
-0.10%+4.60%-10.47%-25.15%-43.88%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
0.00%+0.81%-4.91%-7.60%+22.94%

MarketRank™

CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Incyte Co. stock logo
INCY
Incyte
4.809 of 5 stars
4.22.00.03.41.92.53.1
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
3.812 of 5 stars
1.44.00.82.93.22.51.9
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
3.4165 of 5 stars
3.55.00.00.02.61.71.3
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
4.2624 of 5 stars
2.23.00.03.33.22.52.5

Analyst Ratings

CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Incyte Co. stock logo
INCY
Incyte
2.44
Hold$75.5046.09% Upside
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
2.75
Moderate Buy$128.756.63% Upside
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
3.00
Buy$10.00100.00% Upside
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
2.48
Hold$429.458.04% Upside

Current Analyst Ratings

Latest MKSI, VRTX, INCY, and MX Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
4/24/2024
Incyte Co. stock logo
INCY
Incyte
Oppenheimer
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetOutperform ➝ Outperform$92.00 ➝ $84.00
4/23/2024
Incyte Co. stock logo
INCY
Incyte
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageNeutral
4/18/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Guggenheim
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$445.00 ➝ $450.00
4/17/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
UBS Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$498.00 ➝ $466.00
4/15/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Oppenheimer
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform ➝ Outperform$500.00
4/12/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Canaccord Genuity Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingSell ➝ Sell$371.00
4/11/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Evercore ISI
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeIn-Line ➝ Outperform$438.00
4/11/2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$457.00 ➝ $462.00
4/2/2024
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
Wells Fargo & Company
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetEqual Weight ➝ Equal Weight$115.00 ➝ $120.00
3/25/2024
Incyte Co. stock logo
INCY
Incyte
Royal Bank of Canada
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingSector Perform ➝ Sector Perform$65.00
3/13/2024
Incyte Co. stock logo
INCY
Incyte
Bank of America
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetNeutral ➝ Neutral$69.00 ➝ $67.00
(Data available from 4/28/2021 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Sales & Book Value

CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Incyte Co. stock logo
INCY
Incyte
$3.70B3.14$2.43 per share21.23$23.16 per share2.23
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
$3.62B2.24$39.33 per share3.07$36.96 per share3.27
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
$230.05M0.83N/AN/A$8.89 per share0.56
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$9.87B10.41$14.66 per share27.12$68.22 per share5.83

Profitability & Earnings

CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Incyte Co. stock logo
INCY
Incyte
$597.60M$2.6519.5011.001.2016.17%12.56%9.64%4/30/2024 (Confirmed)
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
-$1.84B-$27.55N/A18.523.97-50.80%9.95%3.05%5/8/2024 (Confirmed)
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
-$36.62M-$0.87N/AN/AN/A-15.92%-7.85%-6.40%5/2/2024 (Confirmed)
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.62B$13.8928.6224.631.8736.68%21.91%16.73%5/6/2024 (Confirmed)

Latest MKSI, VRTX, INCY, and MX Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/8/2024N/A
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
$0.75N/A-$0.75N/AN/AN/A  
5/6/2024N/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.61N/A-$3.61N/AN/AN/A  
5/2/2024N/A
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
-$0.38N/A+$0.38N/AN/AN/A  
4/30/2024N/A
Incyte Co. stock logo
INCY
Incyte
$0.8810N/A-$0.8810N/AN/AN/A  
2/28/2024Q4 2023
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
-$0.34-$0.26+$0.08-$0.36$52.45 million$50.82 million    
2/13/202412/31/2023
Incyte Co. stock logo
INCY
Incyte
$1.15$1.06-$0.09$0.75$1.00 billion$1.01 billion    
2/7/2024Q4 2023
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
$0.89$1.17+$0.28$3.36$845.25 million$893.00 million    
2/5/2024Q4 23
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.85$4.20+$0.35$3.43$2.50 billion$2.52 billion    

Dividends

CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Incyte Co. stock logo
INCY
Incyte
N/AN/AN/AN/AN/A
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
$0.880.73%+3.23%N/A N/A
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
N/AN/AN/AN/AN/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
N/AN/AN/AN/AN/A

Latest MKSI, VRTX, INCY, and MX Dividends

AnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date
2/5/2024
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
quarterly$0.220.8%2/23/20242/26/20243/8/2024
(Data available from 1/1/2013 forward)

Debt

CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Incyte Co. stock logo
INCY
Incyte
0.01
3.55
3.36
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
1.90
3.18
2.01
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
N/A
5.23
4.54
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
0.02
3.99
3.78

Ownership

Institutional Ownership

CompanyInstitutional Ownership
Incyte Co. stock logo
INCY
Incyte
96.97%
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
99.79%
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
74.26%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
90.96%

Insider Ownership

CompanyInsider Ownership
Incyte Co. stock logo
INCY
Incyte
17.50%
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
0.46%
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
4.50%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
0.20%

Miscellaneous

CompanyEmployeesShares OutstandingFree FloatOptionable
Incyte Co. stock logo
INCY
Incyte
2,524224.53 million185.23 millionOptionable
MKS Instruments, Inc. stock logo
MKSI
MKS Instruments
10,20067.06 million66.75 millionOptionable
Magnachip Semiconductor Co. stock logo
MX
Magnachip Semiconductor
89138.26 million36.54 millionOptionable
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
5,400258.46 million257.94 millionOptionable

MKSI, VRTX, INCY, and MX Headlines

SourceHeadline
2 Top Growth Stocks to Buy Right Now and Hold Forever2 Top Growth Stocks to Buy Right Now and Hold Forever
fool.com - April 28 at 8:45 AM
C WorldWide Group Holding A S Lowers Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)C WorldWide Group Holding A S Lowers Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 27 at 5:21 PM
Want $1 Million in Retirement? 3 Stocks to Buy Now And Hold for Decades.Want $1 Million in Retirement? 3 Stocks to Buy Now And Hold for Decades.
fool.com - April 27 at 5:50 AM
Pioneer Institute study finds IRA discourages non-opioid drug innovationPioneer Institute study finds IRA discourages non-opioid drug innovation
pharmaceutical-technology.com - April 26 at 4:37 PM
ALPINE IMMUNE INVESTOR ALERT by the Former Attorney General of Louisiana: Kahn Swick & Foti, LLC Investigates Adequacy of Price and Process in Proposed Sale of Alpine Immune Sciences, Inc. - ALPNALPINE IMMUNE INVESTOR ALERT by the Former Attorney General of Louisiana: Kahn Swick & Foti, LLC Investigates Adequacy of Price and Process in Proposed Sale of Alpine Immune Sciences, Inc. - ALPN
businesswire.com - April 26 at 4:13 PM
Meritage Portfolio Management Purchases 15,006 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Meritage Portfolio Management Purchases 15,006 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 26 at 2:53 PM
The Zacks Analyst Blog Highlights Biogen, Bristol Myers Squibb, Incyte and Vertex PharmaceuticalsThe Zacks Analyst Blog Highlights Biogen, Bristol Myers Squibb, Incyte and Vertex Pharmaceuticals
finance.yahoo.com - April 26 at 10:46 AM
Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Given Consensus Rating of "Hold" by BrokeragesVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Given Consensus Rating of "Hold" by Brokerages
americanbankingnews.com - April 26 at 1:38 AM
Bank Julius Baer & Co. Ltd Zurich Purchases 18,002 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Bank Julius Baer & Co. Ltd Zurich Purchases 18,002 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 25 at 8:34 PM
Vertex Pharmaceuticals (VRTX) Falls More Steeply Than Broader Market: What Investors Need to KnowVertex Pharmaceuticals (VRTX) Falls More Steeply Than Broader Market: What Investors Need to Know
zacks.com - April 25 at 6:56 PM
2 Fantastic Growth Stocks to Buy Right Now2 Fantastic Growth Stocks to Buy Right Now
fool.com - April 25 at 9:45 AM
Yousif Capital Management LLC Sells 2,576 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Yousif Capital Management LLC Sells 2,576 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 24 at 4:00 PM
F M Investments LLC Buys Shares of 4,129 Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)F M Investments LLC Buys Shares of 4,129 Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 23 at 10:08 PM
Vertex hops on to TreeFrog platform to aid diabetes bidVertex hops on to TreeFrog platform to aid diabetes bid
thepharmaletter.com - April 23 at 10:50 AM
Vertex (VRTX), TreeFrog Sign Deal for Diabetes Cell TherapiesVertex (VRTX), TreeFrog Sign Deal for Diabetes Cell Therapies
zacks.com - April 23 at 9:10 AM
Vertex Pharmaceuticals Just Made 2 Big Moves. Is the Stock a Buy?Vertex Pharmaceuticals Just Made 2 Big Moves. Is the Stock a Buy?
fool.com - April 23 at 6:05 AM
VERTEX AND TREEFROG THERAPEUTICS ANNOUNCE LICENSING AGREEMENT AND COLLABORATION TO OPTIMIZE PRODUCTION OF VERTEXS CELL THERAPIES FOR TYPE 1 DIABETESVERTEX AND TREEFROG THERAPEUTICS ANNOUNCE LICENSING AGREEMENT AND COLLABORATION TO OPTIMIZE PRODUCTION OF VERTEX'S CELL THERAPIES FOR TYPE 1 DIABETES
prnewswire.com - April 23 at 12:45 AM
Illinois Municipal Retirement Fund Buys 3,033 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Illinois Municipal Retirement Fund Buys 3,033 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 22 at 9:59 PM
If Youd Invested $10,000 in Vertex Pharmaceuticals 5 Years Ago, Heres How Much Youd Have TodayIf You'd Invested $10,000 in Vertex Pharmaceuticals 5 Years Ago, Here's How Much You'd Have Today
fool.com - April 22 at 7:16 AM
Looking for Once-in-a-Generation Investment Opportunities? Here Are 3 Magnificent Stocks to Buy Right NowLooking for Once-in-a-Generation Investment Opportunities? Here Are 3 Magnificent Stocks to Buy Right Now
fool.com - April 22 at 5:52 AM
Q3 2025 EPS Estimates for Vertex Pharmaceuticals Incorporated Lowered by Zacks Research (NASDAQ:VRTX)Q3 2025 EPS Estimates for Vertex Pharmaceuticals Incorporated Lowered by Zacks Research (NASDAQ:VRTX)
americanbankingnews.com - April 22 at 2:18 AM
Ardevora Asset Management LLP Has $11.54 Million Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Ardevora Asset Management LLP Has $11.54 Million Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 21 at 8:52 PM
Lindbrook Capital LLC Grows Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)Lindbrook Capital LLC Grows Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)
marketbeat.com - April 20 at 1:16 PM
2 Everlasting Big Pharma Stocks to Buy Today and Hold Forever2 Everlasting Big Pharma Stocks to Buy Today and Hold Forever
fool.com - April 20 at 9:45 AM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

All Headlines

Company Descriptions

Incyte logo

Incyte

NASDAQ:INCY
Incyte Corporation, a biopharmaceutical company, engages in the discovery, development, and commercialization of therapeutics for hematology/oncology, and inflammation and autoimmunity areas in the United States and internationally. The company offers JAKAFI (ruxolitinib) for treatment of intermediate or high-risk myelofibrosis, polycythemia vera, and steroid-refractory acute graft-versus-host disease; MONJUVI (tafasitamab-cxix)/MINJUVI (tafasitamab) for relapsed or refractory diffuse large B-cell lymphoma; PEMAZYRE (pemigatinib), a fibroblast growth factor receptor kinase inhibitor that act as oncogenic drivers in liquid and solid tumor types; ICLUSIG (ponatinib) to treat chronic myeloid leukemia and Philadelphia-chromosome positive acute lymphoblastic leukemia; and ZYNYZ (retifanlimab-dlwr) to treat adults with metastatic or recurrent locally advanced Merkel cell carcinoma, as well as OPZELURA cream for treatment of atopic dermatitis. Its clinical stage products include retifanlimab under Phase 3 clinical trials for squamous cell carcinoma of the anal canal and non-small cell lung cancer; axatilimab, an anti-CSF-1R monoclonal antibody under Phase 2 that is being developed as a therapy for patients with chronic GVHD; INCA033989 to inhibit oncogenesis; INCB160058, which is being developed as a disease-modifying therapeutic; and INCB99280 and INCB99318 for the treatment solid tumors. The company also develops INCB123667, INCA32459, and INCA33890, as well as Ruxolitinib cream, Povorcitinib, and INCA034460. It has collaboration out-license agreements with Novartis and Lilly; in-license agreements with Agenus, Merus, MacroGenics, and Syndax; and collaboration and license agreement with China Medical System Holdings Limited for the development and commercialization of povorcitinib. The company sells its products to specialty, retail, and hospital pharmacies, distributors, and wholesalers. The company was formerly known as Incyte Genomics Inc and changed its name to Incyte Corporation in March 2003. Incyte Corporation was incorporated in 1991 and is headquartered in Wilmington, Delaware.
MKS Instruments logo

MKS Instruments

NASDAQ:MKSI
MKS Instruments, Inc. provides foundational technology solutions to semiconductor manufacturing, electronics and packaging, and specialty industrial applications in the United States, Germany, China, South Korea, and internationally. It operates through Vacuum Solutions Division (VSD), Photonics Solutions Division (PSD), and Material Solutions Division (MSD) segments. The VSD segment provides foundational technology solutions, including pressure measurement and control, flow measurement and control, gas and vapor delivery, gas composition analysis, electronic control technology, reactive gas generation and delivery, power generation and delivery, and vacuum technology. The PSD segment offers range of solutions, which include lasers, beam measurement and profiling, precision motion control, vibration isolation systems, photonics instruments, temperature sensing, opto-mechanical components, optical elements, systems for flexible PCB laser processing, and laser-based systems, as well as high density interconnect PCB and package manufacturing. The MSD segment develops, process, and manufactures technologies comprising advanced surface modification, electroless and electrolytic plating, and surface finishing for chemistry, equipment, software, and services markets, as well as high-technology applications. In addition, the company sells its products and services through direct sales, network of independent distributors, and sales representatives, as well as websites, including product catalogs. The company was incorporated in 1961 and is headquartered in Andover, Massachusetts.
Magnachip Semiconductor logo

Magnachip Semiconductor

NYSE:MX
Magnachip Semiconductor Corporation, together with its subsidiaries, designs, manufactures, and supplies analog and mixed-signal semiconductor platform solutions for communications, the Internet of Things, consumer, computing, industrial, and automotive applications. It provides display solutions, including source and gate drivers, and timing controllers that cover a range of flat panel displays used in mobile communications, automotive, entertainment devices, monitors, notebook PCs, tablet PC and TVs applied with liquid crystal display, organic light emitting diodes (OLED), and micro light emitting diode (Micro LED) panel. The company also offers metal oxide semiconductor field-effect transistors, insulated-gate bipolar transistors, AC-DC converters, DC-DC converters, LED drivers, regulators, and power management integrated circuits for a range of devices comprising televisions, smartphones, mobile phones, wearable devices, desktop PCs, notebooks, tablet PCs, and other consumer electronics, as well as for power suppliers, e-bikes, photovoltaic inverters, LED lighting, and motor drives; and OLED display driver integrated circuit products. It serves consumer, computing, communication, automotive and industrial electronics OEMs, original design manufacturers, and electronics manufacturing services companies, as well as subsystem designers in the Asia Pacific, the United States, and Europe. The company sells its products through a direct sales force, as well as through a network of agents and distributors. Magnachip Semiconductor Corporation was incorporated in 2003 and is based in Cheongju, South Korea.
Vertex Pharmaceuticals logo

Vertex Pharmaceuticals

NASDAQ:VRTX
Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.