Spruce Biosciences (SPRB) Stock Chart & Stock Price History $169.30 -6.02 (-3.43%) As of 01:09 PM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Spruce Biosciences Stock Price Performance The Spruce Biosciences (SPRB) stock chart highlights key performance trends across multiple timeframes. Over the last 12 months, the stock's price has increased 407.79%, with a year-to-date return of 428.46%. In the past month, the stock has increased 1,616.13%, reflecting recent market activity. As of the latest close, Spruce Biosciences traded at $175.31 with a market cap of $98.17 million and volume of 346,838 shares. 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Read our full terms of service and privacy policy. 5 Day Performance+1,993.90%1 Month Performance+1,616.13%3 Month Performance+2,923.89%Year-To-Date Performance+428.46%1 Year Performance+407.79% SPRB Stock Chart for Friday, October, 10, 2025 SPRB Chart by TradingView Spruce Biosciences Stock Price History Daily Weekly Monthly Yearly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 3 Year 5 Year Time Frame Start Date End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization10/09/2025$160.07$175.31+9.52%$180.00$140.50346,838 shs$98.17 million10/08/2025$182.60$160.07-12.34%$175.00$138.01758,371 shs$89.64 million10/07/2025$130.40$182.60+40.03%$240.00$175.002.05 million shs$102.62 million10/06/2025$7.95$130.40+1,540.25%$170.00$30.0324.45 million shs$73.02 million10/03/2025$8.51$7.95-6.58%$8.95$7.8824,573 shs$4.45 million10/02/2025$8.77$8.51-2.91%$9.09$8.5511,829 shs$4.77 million10/01/2025$8.95$8.77-2.07%$9.29$8.688,011 shs$4.93 million09/30/2025$9.70$8.95-7.73%$9.78$8.4934,441 shs$5.01 million09/29/2025$7.81$9.70+24.20%$10.20$7.2669,168 shs$5.43 million09/26/2025$7.70$7.81+1.43%$7.97$7.75824 shs$4.37 million Get the Latest News and Ratings for SPRB and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Spruce Biosciences and its competitors with MarketBeat's FREE daily newsletter. 09/25/2025$8.25$7.70-6.61%$8.10$7.696,723 shs$4.31 million09/24/2025$8.50$8.25-3.00%$8.60$7.5020,086 shs$4.77 million09/23/2025$9.08$8.50-6.39%$8.64$8.354,420 shs$4.76 million09/22/2025$8.40$9.08+8.11%$9.64$8.2016,300 shs$5.09 million09/19/2025$8.87$8.40-5.35%$9.00$8.385,091 shs$4.70 million09/18/2025$9.52$8.87-6.79%$9.50$8.882,474 shs$4.99 million09/17/2025$9.58$9.52-0.63%$10.10$8.8710,879 shs$5.33 million09/16/2025$9.80$9.58-2.24%$9.75$8.7016,138 shs$5.38 million09/15/2025$12.40$9.80-20.97%$11.64$8.05102,509 shs$5.51 million09/12/2025$8.80$12.40+40.91%$12.75$8.3275,838 shs$6.97 million09/11/2025$9.70$8.80-9.28%$8.99$8.552,167 shs$4.95 million09/10/2025$9.00$9.70+7.78%$9.86$8.6014,523 shs$5.45 million09/09/2025$9.00$9.00$9.00$8.551,835 shs$5.06 million Related Companies Citius Pharmaceuticals Stock Chart Finch Therapeutics Group Stock Chart Synlogic Stock Chart ProPhase Labs Stock Chart Abpro Stock Chart Lexaria Bioscience Stock Chart Cellectar Biosciences Stock Chart Tharimmune Stock Chart Leap Therapeutics Stock Chart Edesa Biotech Stock Chart Receive SPRB Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spruce Biosciences and its competitors with MarketBeat's FREE daily newsletter. 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