| 8/12/2026 | SR One Capital Management LP | 747,750 | $1.29M | 0.0% | N/A | 1.116% | |
| 5/29/2026 | Perceptive Advisors LLC | 5,827,506 | $39.69M | 0.8% | -0.7% | 8.699% | |
| 5/18/2026 | ADAR1 Capital Management LLC | 133,686 | $910K | 0.1% | -56.0% | 0.200% | |
| 5/18/2026 | Eversept Partners LP | 510,543 | $3.48M | 0.2% | +12.0% | 0.762% | |
| 5/15/2026 | Affinity Asset Advisors LLC | 610,370 | $4.16M | 0.2% | -5.1% | 0.911% | |
| 5/14/2026 | Renaissance Technologies LLC | 156,100 | $1.06M | 0.0% | +651.1% | 0.233% | |
| 5/14/2026 | Siren L.L.C. | 5,253,159 | $35.77M | 1.0% | +57.5% | 7.842% | |
| 5/14/2026 | Sei Investments Co. | 60,036 | $409K | 0.0% | N/A | 0.090% | |
| 5/14/2026 | Monashee Investment Management LLC | 320,000 | $2.18M | 1.2% | +8.5% | 0.478% | |
| 5/7/2026 | Dimensional Fund Advisors LP | 36,873 | $251K | 0.0% | N/A | 0.055% | |
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| 2/18/2026 | XTX Topco Ltd | 23,922 | $216K | 0.0% | N/A | 0.036% | |
| 2/18/2026 | Vestal Point Capital LP | 1,055,000 | $9.53M | 0.3% | +185.1% | 1.575% | |
| 2/18/2026 | Virtus Investment Advisers LLC | 31,445 | $284K | 0.1% | N/A | 0.047% | |
| 2/18/2026 | Quadrature Capital Ltd | 48,583 | $439K | 0.0% | N/A | 0.073% | |
| 2/18/2026 | Perceptive Advisors LLC | 5,869,076 | $53.00M | 0.9% | +179.8% | 8.762% | |
| 2/18/2026 | Millennium Management LLC | 1,499,520 | $13.54M | 0.0% | +7,214.0% | 2.239% | |
| 2/18/2026 | Janus Henderson Group PLC | 1,900,000 | $17.11M | 0.0% | N/A | 2.836% | |
| 2/18/2026 | Elmind Capital LP | 210,000 | $1.90M | 0.6% | N/A | 0.314% | |
| 2/18/2026 | Eversept Partners LP | 455,835 | $4.12M | 0.2% | N/A | 0.681% | |
| 2/18/2026 | Cormorant Asset Management LP | 4,000,000 | $36.12M | 1.7% | +72.1% | 5.971% | |
| 2/17/2026 | ADAR1 Capital Management LLC | 303,686 | $2.74M | 0.2% | N/A | 0.453% | |
| 2/17/2026 | Schonfeld Strategic Advisors LLC | 16,645 | $150K | 0.0% | -33.6% | 0.025% | |
| 2/17/2026 | Braidwell LP | 3,131,319 | $28.28M | 0.9% | +38.2% | 4.674% | |
| 2/17/2026 | MPM Bioimpact LLC | 1,840,898 | $16.62M | 1.9% | +247.1% | 2.748% | |
| 2/17/2026 | Jump Financial LLC | 13,400 | $121K | 0.0% | N/A | 0.020% | |
| 2/17/2026 | Omega Fund Management LLC | 876,357 | $7.91M | 2.8% | +66.5% | 1.308% | |
| 2/17/2026 | Polar Capital Holdings Plc | 1,142,982 | $10.32M | 0.0% | N/A | 1.706% | |
| 2/16/2026 | Kennedy Capital Management LLC | 76,765 | $693K | 0.0% | N/A | 0.115% | |
| 2/16/2026 | Eventide Asset Management LLC | 950,000 | $8.58M | 0.1% | N/A | 1.418% | |
| 2/13/2026 | Affinity Asset Advisors LLC | 643,370 | $5.81M | 0.3% | +735.5% | 0.960% | |
| 2/13/2026 | Siren L.L.C. | 3,336,264 | $30.13M | 0.9% | N/A | 4.980% | |
| 2/13/2026 | Wells Fargo & Company MN | 11,217 | $101K | 0.0% | -37.4% | 0.017% | |
| 2/12/2026 | Jane Street Group LLC | 56,454 | $510K | 0.0% | N/A | 0.084% | |
| 2/12/2026 | HRT Financial LP | 64,380 | $581K | 0.0% | N/A | 0.096% | |
| 2/12/2026 | Renaissance Technologies LLC | 20,782 | $188K | 0.0% | N/A | 0.031% | |
| 2/12/2026 | Monashee Investment Management LLC | 295,000 | $2.66M | 1.5% | N/A | 0.440% | |
| 2/11/2026 | Franklin Resources Inc. | 1,388,000 | $12.53M | 0.0% | +33.7% | 2.072% | |
| 2/9/2026 | Blue Owl Capital Holdings LP | 3,360,937 | $30.35M | 2.3% | +2.5% | 5.017% | |
| 2/3/2026 | Privium Fund Management B.V. | 352,087 | $3.18M | 0.6% | N/A | 0.526% | |
| 1/16/2026 | PFS Partners LLC | 11,000 | $99K | 0.0% | +22.2% | 0.016% | |
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| 12/15/2025 | Hudson Bay Capital Management LP | 11,074 | $76K | 0.0% | N/A | 0.017% | |
| 11/17/2025 | Millennium Management LLC | 20,502 | $140K | 0.0% | +57.3% | 0.040% | |
| 11/17/2025 | Citadel Advisors LLC | 58,370 | $399K | 0.0% | +153.3% | 0.114% | |
| 11/17/2025 | Bank of America Corp DE | 647,192 | $4.42M | 0.0% | -67.7% | 1.264% | |
| 11/17/2025 | Braidwell LP | 2,266,319 | $15.48M | 0.5% | N/A | 4.427% | |
| 11/14/2025 | Schonfeld Strategic Advisors LLC | 25,070 | $171K | 0.0% | -85.6% | 0.049% | |
| 11/14/2025 | Raymond James Financial Inc. | 10,000 | $68K | 0.0% | +383.6% | 0.020% | |
| 11/14/2025 | Deep Track Capital LP | 2,239,353 | $15.30M | 0.4% | -50.9% | 4.375% | |
| 11/13/2025 | Blue Owl Capital Holdings LP | 3,278,106 | $22.39M | 6.9% | -12.1% | 6.404% | |
| 10/16/2025 | PFS Partners LLC | 9,000 | $61K | 0.0% | N/A | 0.018% | |
| 8/15/2025 | Adage Capital Partners GP L.L.C. | 1,000,000 | $3.64M | 0.0% | -36.4% | 1.957% | |
| 8/14/2025 | Paloma Partners Management Co | 10,319 | $38K | 0.0% | N/A | 0.020% | |
| 8/14/2025 | Orbimed Advisors LLC | 677,977 | $2.47M | 0.1% | -24.0% | 1.327% | |
| 8/13/2025 | Affinity Asset Advisors LLC | 77,000 | $280K | 0.0% | N/A | 0.151% | |
| 8/13/2025 | Cresset Asset Management LLC | 10,000 | $36K | 0.0% | N/A | 0.020% | |
| 8/12/2025 | Franklin Resources Inc. | 1,038,000 | $3.78M | 0.0% | -11.6% | 2.031% | |
| 5/16/2025 | Adage Capital Partners GP L.L.C. | 1,571,642 | $7.04M | 0.0% | +2.7% | 3.083% | |
| 5/16/2025 | ADAR1 Capital Management LLC | 23,799 | $107K | 0.0% | N/A | 0.047% | |
| 5/15/2025 | MAI Capital Management | 78,067 | $350K | 0.0% | +11.0% | 0.153% | |
| 2/19/2025 | Toronto Dominion Bank | 14,537 | $97K | 0.0% | N/A | 0.033% | |
| 2/17/2025 | VR Adviser LLC | 5,046,414 | $33.56M | 2.3% | +41.5% | 11.412% | |
| 2/17/2025 | Vestal Point Capital LP | 370,000 | $2.46M | 0.1% | N/A | 0.837% | |
| 2/17/2025 | Two Sigma Investments LP | 35,866 | $239K | 0.0% | -9.5% | 0.081% | |
| 2/17/2025 | Toronto Dominion Bank | 14,537 | $97K | 0.0% | N/A | 0.033% | |
| 2/17/2025 | Sphera Funds Management LTD. | 560,000 | $3.72M | 0.7% | N/A | 1.266% | |
| 2/17/2025 | Point72 Asset Management L.P. | 1,224,797 | $8.15M | 0.0% | +84.7% | 2.770% | |
| 2/17/2025 | Orbimed Advisors LLC | 920,339 | $6.12M | 0.1% | N/A | 2.081% | |
| 2/17/2025 | Omega Fund Management LLC | 526,357 | $3.50M | 2.9% | -51.1% | 1.190% | |
| 2/17/2025 | Fcpm Iii Services B.V. | 9,632,561 | $64.06M | 10.9% | +11.0% | 21.783% | |
| 2/17/2025 | Deep Track Capital LP | 4,557,575 | $30.31M | 1.1% | +74.8% | 10.307% | |
| 2/17/2025 | Corton Capital Inc. | 23,601 | $157K | 0.1% | N/A | 0.053% | |
| 2/17/2025 | Cubist Systematic Strategies LLC | 15,342 | $102K | 0.0% | +15.7% | 0.035% | |
| 2/17/2025 | BVF Inc. IL | 2,106,037 | $14.01M | 0.5% | -6.4% | 4.763% | |
| 2/14/2025 | Jane Street Group LLC | 14,038 | $93K | 0.0% | N/A | 0.032% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 132,260 | $880K | 0.0% | -56.8% | 0.299% | |
| 2/14/2025 | Blue Owl Capital Holdings LP | 3,159,975 | $21.01M | 5.0% | +3.3% | 7.146% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 1,529,768 | $10.17M | 0.0% | -34.3% | 3.459% | |
| 2/13/2025 | Marshall Wace LLP | 593,742 | $3.95M | 0.0% | -12.9% | 1.343% | |
| 1/30/2025 | Vontobel Holding Ltd. | 10,417 | $69K | 0.0% | N/A | 0.024% | |
| 11/27/2024 | Franklin Resources Inc. | 1,189,952 | $7.85M | 0.0% | +48.7% | 2.691% | |
| 11/15/2024 | Point72 Asset Management L.P. | 663,000 | $4.38M | 0.0% | +1,410.3% | 1.499% | |
| 11/4/2024 | Wolverine Asset Management LLC | 5,574 | $37K | 0.0% | N/A | 0.013% | |
| 8/19/2024 | Point72 Asset Management L.P. | 43,900 | $414K | 0.0% | -76.0% | 0.099% | |
| 8/16/2024 | Perceptive Advisors LLC | 800,000 | $7.54M | 0.2% | -19.9% | 1.811% | |
| 8/15/2024 | Blue Owl Capital Holdings LP | 2,449,827 | $23.10M | 6.4% | -0.5% | 5.547% | |
| 8/14/2024 | Marshall Wace LLP | 764,645 | $7.21M | 0.0% | -4.4% | 1.731% | |
| 8/14/2024 | Logos Global Management LP | 1,200,000 | $11.32M | 0.9% | +50.0% | 2.717% | |
| 8/13/2024 | SR One Capital Management LP | 500,000 | $4.72M | 1.5% | N/A | 1.132% | |
| 5/16/2024 | Janus Henderson Group PLC | 1,000,000 | $17.10M | 0.0% | N/A | 2.295% | |
| 5/15/2024 | Altitude Crest Partners Inc. | 120,289 | $2.04M | 0.9% | N/A | 0.276% | |
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| 3/7/2024 | Fcpm Iii Services B.V. | 8,677,951 | $80.10M | 23.8% | N/A | 37.408% | |
| 2/15/2024 | Omega Fund Management LLC | 1,131,175 | $10.44M | 8.5% | N/A | 4.876% | |
| 2/15/2024 | BVF Inc. IL | 2,251,037 | $20.78M | 0.5% | N/A | 9.703% | |
| 2/7/2024 | Vivo Capital LLC | 678,705 | $6.26M | 0.5% | N/A | 2.925% | |