NASDAQ:LXEO Lexeo Therapeutics (LXEO) Stock Price, News & Analysis $3.14 -0.17 (-5.14%) Closing price 04:00 PM EasternExtended Trading$3.16 +0.02 (+0.64%) As of 07:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsInsider TradesNews and TrendsOwnershipSEC FilingsShort Interest About Lexeo Therapeutics Stock (NASDAQ:LXEO) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Lexeo Therapeutics alerts:Sign Up Key Stats Today's Range$3.14▼$3.2950-Day Range$3.14▼$5.3752-Week Range$3.14▼$10.99Volume1.26 million shsAverage Volume978,737 shsMarket Capitalization$257.64 millionP/E RatioN/ADividend YieldN/APrice Target$18.13Consensus RatingBuy Company Overview Lexeo Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing gene therapies for genetic and acquired diseases. The company uses adeno-associated virus (AAV) delivery technology to introduce genetic material intended to address underlying disease mechanisms, with programs spanning central nervous system and cardiovascular conditions. Lexeo’s development portfolio includes investigational therapies for APOE4-associated Alzheimer’s disease, Friedreich’s ataxia, and inherited cardiac disorders such as LMNA-related dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy. Its candidates are in clinical development, and the company’s research and development activities are primarily focused on advancing these therapies through clinical testing and regulatory evaluation. Founded in 2017 and headquartered in New York, Lexeo serves patients through a development program centered largely on the United States. The company is led by Chief Executive Officer R. Nolan Townsend and became a publicly traded company on the Nasdaq under the ticker symbol LXEO in 2023.AI Generated. May Contain Errors. Read More Lexeo Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks50th Percentile Overall ScoreLXEO MarketRank™: Lexeo Therapeutics scored higher than 50% of companies evaluated by MarketBeat, and ranked 550th out of 900 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.3 / 5Analyst RatingBuy Consensus RatingLexeo Therapeutics has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 2 strong buy ratings, 6 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialLexeo Therapeutics has a consensus price target of $18.13, representing about 477.2% upside from its current price of $3.14.Amount of Analyst CoverageLexeo Therapeutics has only been the subject of 4 research reports in the past 90 days.Read more about Lexeo Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Lexeo Therapeutics are expected to decrease in the coming year, from ($1.18) to ($1.44) per share.Price to Book Value per Share RatioLexeo Therapeutics has a P/B Ratio of 0.93. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Lexeo Therapeutics' valuation and earnings. Short Interest0.0 / 5Short Interest LevelBearish Percentage of Shares Shorted25.66% of the float of Lexeo Therapeutics has been sold short.Short Interest Ratio / Days to CoverLexeo Therapeutics has a short interest ratio ("days to cover") of 33.44, which indicates bearish sentiment.Change versus previous monthShort interest in Lexeo Therapeutics has recently increased by 0.70%, indicating that investor sentiment is decreasing. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldLexeo Therapeutics does not currently pay a dividend.Dividend GrowthLexeo Therapeutics does not have a long track record of dividend growth. News and Social Media2.1 / 5News Sentiment0.30 News SentimentLexeo Therapeutics has a news sentiment score of 0.30. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.75 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 13 news articles for Lexeo Therapeutics this week, compared to 3 articles on an average week.MarketBeat FollowsOnly 1 people have added Lexeo Therapeutics to their MarketBeat watchlist in the last 30 days. This is a decrease of -67% compared to the previous 30 days. Company Ownership1.5 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Lexeo Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $299,817.00 in company stock.Percentage Held by Insiders2.00% of the stock of Lexeo Therapeutics is held by insiders.Percentage Held by Institutions60.67% of the stock of Lexeo Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Lexeo Therapeutics' insider trading history. Receive LXEO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Lexeo Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 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LXEO Stock News HeadlinesLeerink Partners Keeps Their Buy Rating on Lexeo Therapeutics, Inc. (LXEO)September 26 at 7:55 AM | theglobeandmail.comLexeo Therapeutics (NASDAQ:LXEO) Earns Outperform Rating from Leerink PartnersSeptember 25 at 1:42 AM | americanbankingnews.comManagement just bought 2.8 million sharesManagement just backed a $100 million buyback, repurchasing 2.8 million shares at an average price of $35.26 in one quarter. Institutions own about 83% of shares, including BlackRock's 32 million shares worth $716 million and Vanguard's 48 million shares worth nearly $1.1 billion. A new multi-year deal with Palantir adds an AI-driven edge to this energy producer's operations.September 28 at 1:00 AM | Monument Traders Alliance (Ad)Apertura Gene Therapy to Provide Lexeo Therapeutics Access to TfR1 CapX™ for Program Designed to Treat Friedreich AtaxiaSeptember 23, 2026 | prnewswire.comLexeo Therapeutics to Participate in the Stifel 2026 Virtual Cardiometabolic ForumSeptember 23, 2026 | globenewswire.comLexeo Therapeutics, Inc. agreed to acquire Mantle Therapeutics Inc. for $21.3 million .September 22, 2026 | marketscreener.comMLexeo Therapeutics to Acquire Mantle Therapeutics for Up to $21.3 Million; Enters Three Research CollaborationsSeptember 22, 2026 | finance.yahoo.comLexeo Therapeutics Signs Series Of Strategic Transactions To Expand Presence In Friedreich AtaxiaSeptember 22, 2026 | rttnews.comSee More Headlines LXEO Stock Analysis - Frequently Asked Questions How have LXEO shares performed this year? Lexeo Therapeutics' stock was trading at $9.93 at the beginning of 2026. Since then, LXEO stock has decreased by 68.4% and is now trading at $3.14. How were Lexeo Therapeutics' earnings last quarter? Lexeo Therapeutics, Inc. (NASDAQ:LXEO) issued its quarterly earnings data on Wednesday, August, 12th. The company reported ($0.30) earnings per share (EPS) for the quarter, missing the consensus estimate of ($0.29) by $0.01. When did Lexeo Therapeutics IPO? Lexeo Therapeutics (LXEO) raised $127 million in an initial public offering on Friday, November 3rd 2023. The company issued 9,090,910 shares at $13.00-$15.00 per share. Who are Lexeo Therapeutics' major shareholders? Top institutional shareholders of Lexeo Therapeutics include Montanova Capital LLC (7.78%), BlackRock Inc. (7.31%), Frazier Life Sciences Management L.P. (5.88%) and Jupiter Topco LLC (5.04%). Insiders that own company stock include Fund Vi LP Omega, Richard Nolan Townsend, Jose Manuel Otero, Louis Edward Tamayo, Narinder Pal Bhalla, Eric Adler and Tai Sandi See. View institutional ownership trends. How do I buy shares of Lexeo Therapeutics? Shares of LXEO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Lexeo Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Lexeo Therapeutics investors own include Tesla (TSLA), NVIDIA (NVDA), Advanced Micro Devices (AMD), JPMorgan Chase & Co. (JPM), Meta Platforms (META), Netflix (NFLX) and Home Depot (HD). Company Calendar Last Earnings8/12/2026Today9/28/2026Stifel 2026 Virtual Cardiometabolic Forum9/30/2026Next Earnings (Estimated)12/14/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (4m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 LXEO's financial health is in the Yellow zone, according to TradeSmith. LXEO has been in this zone for over 4 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:LXEO Previous SymbolNASDAQ:LXEO CIK1907108 Webwww.lexeotx.com Phone212-547-9879FaxN/AEmployees59Year Founded2018Price Target and Rating Average Price Target for Lexeo Therapeutics$18.13 High Price Target$30.00 Low Price Target$9.00 Potential Upside/Downside+477.2%Consensus RatingBuy Rating Score (0-4)3.00 Research Coverage9 Analysts Profitability EPS (Trailing Twelve Months)($1.15) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$99.96 million Net MarginsN/A Pretax MarginN/A Return on Equity-41.85% Return on Assets-38.03% Debt Debt-to-Equity RatioN/A Current Ratio13.89 Quick Ratio13.89 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$3.38 per share Price / Book0.93Miscellaneous Outstanding Shares82,050,000Free Float80,405,000Market Cap$257.64 million OptionableNot Optionable Beta1.50 Social Links The Infrastructure's Backbone: 10 Stocks Powering the AI BuildoutThe AI boom extends far beyond the biggest tech names. Discover 10 companies supplying the memory, storage, networking, semiconductor manufacturing, and power infrastructure that make AI possible. Learn where the next wave of AI investment opportunities may emerge—and the key risks investors should watch as the global AI buildout accelerates.Get This Free Report This page (NASDAQ:LXEO) was last updated on 9/28/2026 by MarketBeat.com Staff. From Our PartnersTrump's New DollarPorter Stansberry says President Trump has signed an executive order initiating what he calls a full U.S. doll...Porter & Company | SponsoredManagement just bought 2.8 million sharesManagement just backed a $100 million buyback, repurchasing 2.8 million shares at an average price of $35.26 i...Monument Traders Alliance | SponsoredElon Musk’s Hushed FCC Filing. 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