Two Sigma Investments, Lp Top Holdings and 13F Report (2024) About Two Sigma Investments, LpInvestment ActivityTwo Sigma Investments, Lp has $46.79 billion in total holdings as of September 30, 2024.Two Sigma Investments, Lp owns shares of 3,109 different stocks, but just 484 companies or ETFs make up 80% of its holdings.Approximately 35.64% of the portfolio was purchased this quarter.About 29.89% of the portfolio was sold this quarter.This quarter, Two Sigma Investments, Lp has purchased 3,107 new stocks and bought additional shares in 1,231 stocks.Two Sigma Investments, Lp sold shares of 1,318 stocks and completely divested from 472 stocks this quarter.Largest Holdings SPDR S&P 500 ETF Trust $842,851,373Technology Select Sector SPDR Fund $431,274,982Invesco QQQ $425,612,893Vanguard Growth ETF $378,570,138iShares Russell 1000 Growth ETF $375,750,254 Largest New Holdings this Quarter 007903107 - Advanced Micro Devices $230,851,848 Holding988498101 - Yum! Brands $108,533,238 Holding165167735 - Chesapeake Energy $96,640,900 Holding81369Y100 - Materials Select Sector SPDR Fund $90,029,658 Holding65339KCY4 - NEXTERA ENERGY CAP HLDGS INC $88,563,730 Holding Largest Purchases this Quarter Broadcom 1,501,252 shares (about $251.35M)PALANTIR TECHNOLOGIES INC 2,761,640 shares (about $233.08M)Advanced Micro Devices 2,246,952 shares (about $230.85M)Salesforce 845,109 shares (about $226.79M)Regeneron Pharmaceuticals 337,528 shares (about $214.07M) Largest Sales this Quarter Progressive 931,705 shares (about $263.68M)Eli Lilly and Company 306,957 shares (about $253.52M)Visa 702,095 shares (about $246.06M)Elevance Health 473,931 shares (about $206.14M)Intel 8,212,751 shares (about $186.51M) Sector Allocation Over TimeMap of 500 Largest Holdings ofTwo Sigma Investments, Lp Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorSPYSPDR S&P 500 ETF Trust$842,851,373$74,476,066 ▼-8.1%1,506,7331.8%FinanceXLKTechnology Select Sector SPDR Fund$431,274,982$169,768,062 ▲64.9%2,088,7010.9%ETFQQQInvesco QQQ$425,612,893$49,674,102 ▼-10.5%907,6450.9%FinanceVUGVanguard Growth ETF$378,570,138$58,070,412 ▲18.1%1,020,9000.8%ETFIWFiShares Russell 1000 Growth ETF$375,750,254$29,826,034 ▲8.6%1,040,6000.8%ETFIVViShares Core S&P 500 ETF$314,102,100$618,090 ▼-0.2%559,0000.7%ETFCMECME Group$270,246,944$4,856,399 ▼-1.8%1,018,6850.6%FinanceAVGOBroadcom$261,133,204$251,354,622 ▲2,570.5%1,559,6560.6%Computer and TechnologyCRMSalesforce$259,161,693$226,793,452 ▲700.7%965,7240.6%Computer and TechnologyLMTLockheed Martin$253,704,031$37,750,569 ▲17.5%567,9390.5%AerospaceNVDANVIDIA$252,855,417$55,479,722 ▲28.1%2,333,0450.5%Computer and TechnologyCHENIERE ENERGY INC$247,783,583$2,282,530 ▼-0.9%1,070,8020.5%COM NEWBSXBoston Scientific$246,222,557$171,385,032 ▲229.0%2,440,7470.5%MedicalGOOGLAlphabet$245,763,630$34,618,484 ▲16.4%1,589,2630.5%Computer and TechnologyMRVLMarvell Technology$242,073,969$183,912,854 ▲316.2%3,931,6870.5%Computer and TechnologySNOWSnowflake$240,923,274$33,712,535 ▲16.3%1,648,3530.5%Computer and TechnologyCORCencora$238,771,411$30,179,439 ▲14.5%858,6120.5%MedicalMSCIMSCI$238,442,510$93,080,169 ▲64.0%421,6490.5%FinancePALANTIR TECHNOLOGIES INC$237,731,421$233,082,416 ▲5,013.6%2,816,7230.5%CL AADBEAdobe$237,611,409$63,918,343 ▲36.8%619,5380.5%Computer and TechnologyREGNRegeneron Pharmaceuticals$235,978,590$214,070,383 ▲977.1%372,0710.5%MedicalRBLXRoblox$233,152,947$30,006,934 ▼-11.4%3,999,8790.5%Consumer DiscretionaryTSLATesla$232,556,708$77,251,450 ▲49.7%897,3480.5%Auto/Tires/TrucksAAPLApple$232,526,128$18,614,494 ▼-7.4%1,046,8020.5%Computer and TechnologyAMDAdvanced Micro Devices$230,851,848$230,851,848 ▲New Holding2,246,9520.5%Computer and TechnologyDOORDASH INC$230,596,705$48,211,802 ▼-17.3%1,261,6770.5%CL AXLVHealth Care Select Sector SPDR Fund$227,702,595$118,539,241 ▼-34.2%1,559,5000.5%ETFHUMHumana$226,702,930$71,368,706 ▲45.9%856,7760.5%MedicalDHRDanaher$226,648,205$16,011,730 ▲7.6%1,105,6010.5%MedicalDGDollar General$224,825,579$17,826,489 ▲8.6%2,556,8700.5%Retail/WholesaleMSFTMicrosoft$223,264,704$2,257,971 ▼-1.0%594,7540.5%Computer and TechnologyMAMastercard$222,768,575$9,380,526 ▼-4.0%406,4230.5%Business ServicesITGartner$219,633,152$182,055,089 ▲484.5%523,2600.5%Business ServicesMCKMcKesson$219,350,323$108,481,277 ▲97.8%325,9340.5%MedicalNVONovo Nordisk A/S$218,592,190$90,515,457 ▲70.7%3,147,9290.5%MedicalIQVIQVIA$216,215,202$80,820,504 ▲59.7%1,226,4050.5%MedicalCNCCentene$215,905,159$79,580,186 ▲58.4%3,556,3360.5%MedicalMELIMercadoLibre$215,042,449$201,478,050 ▲1,485.3%110,2290.5%Retail/WholesaleARISTA NETWORKS INC$214,391,654$178,743,803 ▲501.4%2,767,0580.5%COM SHSICEIntercontinental Exchange$213,727,845$42,548,505 ▲24.9%1,239,0020.5%FinanceISRGIntuitive Surgical$203,883,343$170,051,449 ▲502.6%411,6610.4%MedicalFTNTFortinet$201,964,935$6,323,127 ▼-3.0%2,098,1190.4%Computer and TechnologyLINDE PLC$200,097,149$139,972,315 ▲232.8%429,7250.4%SHSMRKMerck & Co., Inc.$197,534,922$24,403,231 ▲14.1%2,200,7010.4%MedicalNFLXNetflix$196,985,772$63,821,421 ▼-24.5%211,2380.4%Consumer DiscretionaryWCNWaste Connections$195,839,592$5,929,287 ▲3.1%1,003,3280.4%Business ServicesNOCNorthrop Grumman$191,618,206$35,541,686 ▼-15.6%374,2470.4%AerospaceNOWServiceNow$189,827,641$186,320,644 ▲5,312.8%238,4350.4%Computer and TechnologySPLGSPDR Portfolio S&P 500 ETF$189,303,312$36,753,264 ▼-16.3%2,878,7000.4%ETFMETAMeta Platforms$189,268,555$44,866,168 ▼-19.2%328,3860.4%Computer and TechnologyCOPConocoPhillips$182,378,887$180,977,080 ▲12,910.3%1,736,6110.4%EnergyVTIVanguard Total Stock Market ETF$182,308,793$22,130,941 ▼-10.8%663,3270.4%ETFLHXL3Harris Technologies$180,333,752$84,089,246 ▲87.4%861,5630.4%AerospaceCMCSAComcast$179,957,573$135,525,656 ▲305.0%4,876,8990.4%Consumer DiscretionaryDHID.R. Horton$171,932,519$60,357,637 ▲54.1%1,352,4150.4%ConstructionIYWiShares U.S. Technology ETF$171,073,335$67,439,288 ▲65.1%1,218,1240.4%ManufacturingVRSKVerisk Analytics$169,801,139$48,408,786 ▲39.9%570,5300.4%Business ServicesOXYOccidental Petroleum$169,307,663$132,493,790 ▲359.9%3,430,0580.4%EnergyTMOThermo Fisher Scientific$164,835,474$59,995,632 ▼-26.7%331,2610.4%MedicalQCOMQUALCOMM$162,400,947$78,440,025 ▼-32.6%1,057,2290.3%Computer and TechnologyKRESPDR S&P Regional Banking ETF$159,004,106$82,614,761 ▲108.1%2,796,9060.3%ETFNETCloudflare$155,964,876$119,305,241 ▲325.4%1,384,0170.3%Computer and TechnologyMSIMotorola Solutions$155,025,019$52,248,246 ▲50.8%354,0920.3%Computer and TechnologySCHWCharles Schwab$152,348,693$100,508,389 ▲193.9%1,946,2020.3%FinanceMLMMartin Marietta Materials$150,872,009$37,477,742 ▲33.1%315,5460.3%ConstructionAMCRAmcor$148,805,721$139,500,986 ▲1,499.2%15,340,7960.3%IndustrialsWMWaste Management$148,721,792$12,511,726 ▲9.2%642,3990.3%Business ServicesCCLCarnival Co. &$147,251,532$87,067,005 ▼-37.2%7,539,7610.3%Consumer DiscretionaryGDGeneral Dynamics$146,824,944$42,263,256 ▼-22.4%538,6490.3%AerospaceTWLOTwilio$141,877,465$31,266,090 ▲28.3%1,449,0600.3%Computer and TechnologyKDPKeurig Dr Pepper$139,426,721$26,100,278 ▲23.0%4,074,4220.3%Consumer StaplesAMZNAmazon.com$138,456,007$90,282,556 ▼-39.5%727,7200.3%Retail/WholesalePANWPalo Alto Networks$137,789,070$68,337,737 ▲98.4%807,4840.3%Computer and TechnologySESEA$135,605,860$11,233,754 ▲9.0%1,039,2050.3%Computer and TechnologyCAHCardinal Health$135,595,714$5,607,101 ▲4.3%984,2180.3%MedicalXLUUtilities Select Sector SPDR Fund$134,336,745$35,916,175 ▼-21.1%1,703,7000.3%ETFTEAMAtlassian$133,861,856$36,405,262 ▲37.4%630,7990.3%Computer and TechnologySPOTSpotify Technology$132,550,630$61,076,431 ▼-31.5%240,9880.3%Business ServicesAMATApplied Materials$132,085,322$63,475,488 ▼-32.5%910,1800.3%Computer and TechnologyHUBSHubSpot$131,983,415$50,164,975 ▲61.3%231,0270.3%Computer and TechnologyEIXEdison International$129,901,631$124,731,224 ▲2,412.4%2,204,7120.3%UtilitiesETREntergy$128,367,851$41,130,008 ▲47.1%1,501,5540.3%UtilitiesRSGRepublic Services$127,057,962$22,726,232 ▲21.8%524,6860.3%Business ServicesEFXEquifax$126,791,734$95,889,572 ▲310.3%520,5770.3%Business ServicesMRNAModerna$126,273,820$107,448,286 ▲570.8%4,454,1030.3%MedicalBAHBooz Allen Hamilton$124,011,069$117,689,208 ▲1,861.6%1,185,8010.3%Business ServicesCVNACarvana$122,876,943$116,792,506 ▼-48.7%587,7030.3%Retail/WholesaleBIIBBiogen$120,327,517$3,693,859 ▲3.2%879,3300.3%MedicalCBOECboe Global Markets$119,232,201$4,553,860 ▼-3.7%526,9000.3%Financial ServicesORCLOracle$119,127,208$117,267,735 ▲6,306.5%852,0650.3%Computer and TechnologyEQIXEquinix$118,671,746$104,447,150 ▲734.3%145,5470.3%FinanceCSXCSX$118,424,525$95,276,829 ▲411.6%4,023,9390.3%TransportationWSTWest Pharmaceutical Services$117,050,509$100,038,316 ▲588.0%522,8270.3%MedicalCOSTCostco Wholesale$116,349,856$43,390,495 ▼-27.2%123,0200.2%Retail/WholesaleCIThe Cigna Group$116,181,744$135,470,356 ▼-53.8%353,1360.2%MedicalADCAgree Realty$115,586,081$43,951,214 ▲61.4%1,497,4230.2%FinanceVEEVVeeva Systems$115,538,665$35,732,865 ▲44.8%498,8070.2%MedicalFFord Motor$115,382,051$110,226,992 ▲2,138.2%11,503,6940.2%Auto/Tires/TrucksMNSTMonster Beverage$114,712,074$71,153,766 ▲163.4%1,960,2200.2%Consumer StaplesAMGNAmgen$112,007,210$169,099,994 ▼-60.2%359,5160.2%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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