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First Trust Multi-Manager Small Cap Opportunities ETF (MMSC) Holdings List

$26.86 -0.41 (-1.50%)
Closing price 04:10 PM Eastern
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$26.88 +0.02 (+0.07%)
As of 04:15 PM Eastern
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What stocks does MMSC hold?

The First Trust Multi-Manager Small Cap Opportunities ETF (MMSC) top stock holdings include Twist Bioscience, Xometry, and JFrog. The top 25 MMSC holdings ordered by weight make up 28.47% of the total fund. MMSC is an equity fund in the size and style category that invests in publicly traded companies and other investments, focused on small cap strategies within the North America region. This page includes a complete MMSC stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 MMSC Holdings

RankCompanyCurrent PriceWeightShares Held
1
Twist Bioscience Corporation stock logo
TWST
Twist Bioscience
$158.50
-3.7%
1.75%5,947
2
Xometry, Inc. stock logo
XMTR
Xometry
$105.01
-0.1%
1.74%9,625
3
JFrog Ltd. stock logo
FROG
JFrog
$92.33
+2.6%
1.61%9,054
4
Travere Therapeutics, Inc. stock logo
TVTX
Travere Therapeutics
$59.83
-0.7%
1.58%12,863
5
Zeta Global Holdings Corp. stock logo
ZETA
Zeta Global
$29.82
-1.0%
1.51%26,188
6
Guardant Health, Inc. stock logo
GH
Guardant Health
$176.31
-0.5%
1.46%4,210
7
FirstCash Holdings, Inc. stock logo
FCFS
FirstCash
$216.47
-2.0%
1.43%3,441
8Morgan Stanley Instl Lqudty Trs InstlN/A1.16%612,427
9
Varonis Systems, Inc. stock logo
VRNS
Varonis Systems
$48.35
+2.2%
1.13%12,442
10
Protagonist Therapeutics, Inc. stock logo
PTGX
Protagonist Therapeutics
$138.70
-4.4%
1.07%3,932
11
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
$88.17
-4.1%
1.07%6,092
12
Rubrik, Inc. stock logo
RBRK
Rubrik
$116.04
+3.7%
1.07%5,215
13
VSE Corporation stock logo
VSEC
VSE
$178.54
-2.7%
1.03%3,117
14
SailPoint, Inc. stock logo
SAIL
SailPoint
$21.41
+0.2%
1.00%26,126
15
Ligand Pharmaceuticals Incorporated stock logo
LGND
Ligand Pharmaceuticals
$298.41
0.0%
1.00%1,850
16
Praxis Precision Medicines, Inc. stock logo
PRAX
Praxis Precision Medicines
$282.12
-6.2%
0.98%1,663
17
Halozyme Therapeutics, Inc. stock logo
HALO
Halozyme Therapeutics
$112.44
-2.3%
0.96%4,615
18
Repligen Corporation stock logo
RGEN
Repligen
$184.53
-1.2%
0.96%2,827
19
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$41.05
-7.8%
0.92%10,290
20
EZCORP, Inc. stock logo
EZPW
EZCORP
$30.19
-1.7%
0.90%15,009
21
Silicon Motion Technology Corporation stock logo
SIMO
Silicon Motion Technology
$276.53
-2.4%
0.87%1,818
22
Definium Therapeutics, Inc. stock logo
DFTX
Definium Therapeutics
$37.65
-6.6%
0.86%11,730
23
Manhattan Associates, Inc. stock logo
MANH
Manhattan Associates
$210.37
+1.6%
0.81%2,017
24
Exelixis, Inc. stock logo
EXEL
Exelixis
$56.73
-2.4%
0.80%7,255
25
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$36.56
-6.5%
0.80%7,332

MMSC Geographic Exposure

MMSC's largest geographic exposure is United States at 86.8%, followed by Canada at 3.3%.

  • United States
    86.8%
  • Canada
    3.3%
  • Israel
    2.2%
  • Cayman Islands
    1.6%
  • Ireland
    0.9%
  • Guernsey
    0.6%
  • United Kingdom
    0.5%
  • Switzerland
    0.4%
  • Jersey
    0.3%

MMSC Currency Exposure

MMSC's largest currency exposure is USD at 72.5%, followed by EUR at 0.5%.

  • USD
    72.5%
  • EUR
    0.5%
  • CAD
    0.4%

MMSC Sector Exposure

MMSC's largest sector exposure is Health Care at 24.2%, followed by Technology at 21.3%.

  • Health Care
    24.2%
  • Technology
    21.3%
  • Industrials
    16.2%
  • Consumer Discretionary
    10.9%
  • Financials
    10.5%
  • Energy
    3.4%
  • Consumer Staples
    3.0%
  • Materials
    1.4%
  • Communications
    1.1%
  • Real Estate
    0.4%

MMSC Industry Exposure

MMSC's largest industry exposure is Biotechnology at 16.0%, followed by Software at 11.2%.

  • Biotechnology
    16.0%
  • Software
    11.2%
  • Semiconductors & Semiconductor Equipment
    6.6%
  • Specialty Retail
    4.0%
  • Aerospace & Defense
    3.8%
  • Diversified Consumer Services
    3.4%
  • Health Care Equipment & Supplies
    3.2%
  • Hotels, Restaurants & Leisure
    3.1%
  • Capital Markets
    2.9%
  • Machinery
    2.7%
  • Other
    35.4%

MMSC Sub-Industry Exposure

MMSC's largest sub-industry exposure is Biotechnology at 15.5%, followed by Application Software at 8.4%.

  • Biotechnology
    15.5%
  • Application Software
    8.4%
  • Semiconductors
    5.5%
  • Systems Software
    4.0%
  • Consumer Finance
    3.8%
  • Aerospace & Defense
    3.8%
  • Pharmaceuticals
    2.9%
  • Electrical Components & Equipment
    2.6%
  • Trading Companies & Distributors
    2.5%
  • Oil & Gas Equipment & Services
    2.5%
  • Other
    38.0%

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MarketBeat tracks First Trust Multi-Manager Small Cap Opportunities ETF holdings and portfolio composition, last updated on 9/20/2026.
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