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First Trust Multi-Manager Small Cap Opportunities ETF (MMSC) Holdings List

$26.38 -0.16 (-0.60%)
Closing price 10/13/2026 04:10 PM Eastern
Extended Trading
$26.39 +0.01 (+0.04%)
As of 10/13/2026 07:30 PM Eastern
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What stocks does MMSC hold?

The First Trust Multi-Manager Small Cap Opportunities ETF (MMSC) has 219 holdings, with Twist Bioscience, Xometry, and Travere Therapeutics among its largest positions. The top 25 MMSC holdings ordered by weight make up 28.50% of the total fund. MMSC is an equity fund in the size and style category that invests in publicly traded companies and other investments, focused on small cap strategies within the North America region. This page includes a complete MMSC stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 MMSC Holdings

RankCompanyCurrent PriceWeightShares Held
1
Twist Bioscience Corporation stock logo
TWST
Twist Bioscience
$151.33
-0.3%
2.09%5,865
2
Xometry, Inc. stock logo
XMTR
Xometry
$107.90
-0.1%
1.93%9,649
3
Travere Therapeutics, Inc. stock logo
TVTX
Travere Therapeutics
$51.80
-0.4%
1.48%12,888
4
Guardant Health, Inc. stock logo
GH
Guardant Health
$162.09
-0.4%
1.43%4,204
5
Zeta Global Holdings Corp. stock logo
ZETA
Zeta Global
$33.80
+0.9%
1.42%25,691
6
FirstCash Holdings, Inc. stock logo
FCFS
FirstCash
$218.83
+1.2%
1.40%3,443
7
JFrog Ltd. stock logo
FROG
JFrog
$99.28
+0.3%
1.36%7,873
8
Varonis Systems, Inc. stock logo
VRNS
Varonis Systems
$48.72
+5.1%
1.21%13,442
9
Protagonist Therapeutics, Inc. stock logo
PTGX
Protagonist Therapeutics
$138.49
-4.4%
1.13%4,201
10
Rubrik, Inc. stock logo
RBRK
Rubrik
$118.58
-1.2%
1.11%5,071
11
Ligand Pharmaceuticals Incorporated stock logo
LGND
Ligand Pharmaceuticals
$303.53
-2.4%
1.11%1,874
12
Repligen Corporation stock logo
RGEN
Repligen
$175.42
+1.7%
1.06%2,832
13
SailPoint, Inc. stock logo
SAIL
SailPoint
$19.37
-1.0%
1.04%26,171
14
Halozyme Therapeutics, Inc. stock logo
HALO
Halozyme Therapeutics
$109.62
-1.3%
1.03%4,810
15
VSE Corporation stock logo
VSEC
VSE
$163.33
-2.5%
1.02%3,119
16
Silicon Motion Technology Corporation stock logo
SIMO
Silicon Motion Technology
$246.63
-0.1%
1.00%1,899
17
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
$80.45
-6.3%
0.99%6,084
18
Praxis Precision Medicines, Inc. stock logo
PRAX
Praxis Precision Medicines
$243.34
-3.2%
0.89%1,660
19
EZCORP, Inc. stock logo
EZPW
EZCORP
$33.07
+1.3%
0.87%15,075
20
Ollie's Bargain Outlet Holdings, Inc. stock logo
OLLI
Ollie's Bargain Outlet
$88.33
+2.2%
0.86%5,164
21
Definium Therapeutics, Inc. stock logo
DFTX
Definium Therapeutics
$34.38
-2.3%
0.86%11,714
22Morgan Stanley Instl Lqudty Trs InstlN/A0.83%433,705
23
Exelixis, Inc. stock logo
EXEL
Exelixis
$59.51
-0.5%
0.82%7,267
24
DigitalOcean Holdings, Inc. stock logo
DOCN
DigitalOcean
$128.41
-2.3%
0.79%3,062
25
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$36.28
-5.6%
0.77%10,276

MMSC Geographic Exposure

MMSC's largest geographic exposure is United States at 86.9%, followed by Canada at 3.1%.

  • United States
    86.9%
  • Canada
    3.1%
  • Israel
    2.3%
  • Cayman Islands
    1.4%
  • Ireland
    0.9%
  • Guernsey
    0.5%
  • United Kingdom
    0.5%
  • Switzerland
    0.4%
  • Marshall Islands
    0.3%
  • Jersey
    0.3%

MMSC Currency Exposure

MMSC's largest currency exposure is USD at 73.2%, followed by EUR at 0.6%.

  • USD
    73.2%
  • EUR
    0.6%
  • CAD
    0.4%

MMSC Sector Exposure

MMSC's largest sector exposure is Technology at 23.7%, followed by Health Care at 22.5%.

  • Technology
    23.7%
  • Health Care
    22.5%
  • Industrials
    15.5%
  • Financials
    10.5%
  • Consumer Discretionary
    10.5%
  • Energy
    4.0%
  • Consumer Staples
    3.3%
  • Materials
    1.3%
  • Communications
    1.1%
  • Real Estate
    0.3%

MMSC Industry Exposure

MMSC's largest industry exposure is Biotechnology at 15.1%, followed by Software at 11.5%.

  • Biotechnology
    15.1%
  • Software
    11.5%
  • Semiconductors & Semiconductor Equipment
    7.5%
  • Aerospace & Defense
    3.6%
  • Hotels, Restaurants & Leisure
    3.5%
  • Specialty Retail
    3.4%
  • Diversified Consumer Services
    3.3%
  • Oil, Gas & Consumable Fuels
    3.0%
  • Capital Markets
    2.8%
  • IT Services
    2.8%
  • Other
    36.3%

MMSC Sub-Industry Exposure

MMSC's largest sub-industry exposure is Biotechnology at 14.9%, followed by Application Software at 9.1%.

  • Biotechnology
    14.9%
  • Application Software
    9.1%
  • Semiconductors
    6.5%
  • Consumer Finance
    3.8%
  • Systems Software
    3.6%
  • Aerospace & Defense
    3.6%
  • Trading Companies & Distributors
    3.0%
  • Oil & Gas Equipment & Services
    2.9%
  • Electrical Components & Equipment
    2.5%
  • Pharmaceuticals
    2.3%
  • Other
    37.8%

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MarketBeat tracks First Trust Multi-Manager Small Cap Opportunities ETF holdings and portfolio composition, last updated on 10/2/2026.
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